Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes (Q33979897)

30 July 2017

title

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes (English)

1 reference

extrachromosomal inheritance

30 July 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:293670

28 February 2023

1

R. J. Kaufman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:293670

15 June 2022

author name string

P. C. Brown

series ordinal

2

0 references

R. T. Schimke

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:293670

28 February 2023

language of work or name

English

0 references

publication date

1 November 1979

1 reference

full work available at URL

30 July 2017

https://europepmc.org/articles/PMC411711

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:293670

https://europepmc.org/articles/PMC411711?pdf=render

28 February 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:293670

https://pnas.org/doi/pdf/10.1073/pnas.76.11.5669

28 February 2023

1 reference

Crossref

DOI

10.1073/PNAS.76.11.5669

https://api.crossref.org/works/10.1073/PNAS.76.11.5669

Proceedings of the National Academy of Sciences of the United States of America

28 February 2023

published in

1 reference

30 July 2017

volume

76

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30 July 2017

issue

11

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30 July 2017

page(s)

5669-5673

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Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells.

30 July 2017

cites work

1 reference

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5 July 2018

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The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis

5 July 2018

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Loss of resistance to methotrexate in L5178Y mouse leukemia grown in vitro

5 July 2018

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Isolation of high-molecular-weight DNA from mammalian cells

5 July 2018

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Detection of specific sequences among DNA fragments separated by gel electrophoresis

5 July 2018

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Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

5 July 2018

1 reference

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Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis

5 July 2018

1 reference

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Synthesis and degradation of folate reductase in sensitive and methotrexate-resistant lines of S-180 cells

5 July 2018

1 reference

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Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

5 July 2018

1 reference

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Gene amplification and drug resistance in cultured murine cells.

5 July 2018

1 reference

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Quantitation of dihydrofolate reductase in individual parental and methotrexate-resistant murine cells. Use of a fluorescence activated cell sorter

5 July 2018

1 reference

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Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells

5 July 2018

1 reference

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Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase

5 July 2018

1 reference

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Chapter 10 Analytical Techniques for Isolated Metaphase Chromosome Fractions

5 July 2018

1 reference

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Studies on the Amplification of Dihydrofolate Reductase Genes in Methotrexate-resistant Cultured Mouse Cells

5 July 2018

1 reference

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Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line

5 July 2018

1 reference

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Amplification of Dihydrofolate Reductase Genes in Methotrexate-resistant Cultured Mouse Cells

5 July 2018

1 reference

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Studies on simian virus 40 excision from cellular chromosomes

5 July 2018

1 reference

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Polyoma virus and cyclic AMP-mediated control of dihydrofolate reductase mRNA abundance in methotrexate-resistant mouse fibroblasts

5 July 2018

1 reference

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A new chromosome type replacing the double minutes in a mouse tumor

5 July 2018

1 reference

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Double Minute Chromosomes and the Homogeneously Staining Regions in Chromosomes of a Human Neuroblastoma Cell Line

5 July 2018

1 reference

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Growth and nucleic acid synthesis in synchronously dividing populations of HeLa cells

5 July 2018

1 reference

12 December 2020

Are double minutes chromosomes?

1 reference

12 December 2020

Have double minutes functioning centromeres?

1 reference

12 December 2020

Experimental elimination and recovery of double minute chromosomes in malignant cell populations

1 reference

12 December 2020

Double minute chromosomes are not centromeric regions of the host chromosomes

1 reference

12 December 2020

Measurements of mammalian cellular DNA and its localization in chromosomes

1 reference

12 December 2020

Altered regulation of the rate of synthesis of dihydrofolate reductase in methotrexate-resistant hamster cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.76.11.5669

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference