Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. (Q33965304)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522 AND SRC:MED&resulttype=core&format=json

2 November 2019

title

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions (English)

1 reference

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2 November 2019

corrigendum / erratum

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10

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2 November 2019

author name string

Juliet A Williams

1

1 reference

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2 November 2019

Oivin M Guicherit

2

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2 November 2019

Beatrice I Zaharian

3

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2 November 2019

Yin Xu

4

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2 November 2019

Ling Chai

5

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2 November 2019

Hynek Wichterle

6

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2 November 2019

Charlene Kon

7

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2 November 2019

Christine Gatchalian

8

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2 November 2019

Jeffery A Porter

9

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2 November 2019

Frank Y Wang

11

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2 November 2019

language of work or name

English

0 references

publication date

4 April 2003

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

2 November 2019

published in

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2 November 2019

volume

100

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2 November 2019

issue

8

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2 November 2019

page(s)

4616-4621

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Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

2 November 2019

cites work

1 reference

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Small molecule modulation of Smoothened activity

28 July 2018

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TGF-beta signaling: positive and negative effects on tumorigenesis

28 July 2018

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Hedgehog signaling in animal development: paradigms and principles

28 July 2018

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The Hedgehog and Wnt signalling pathways in cancer

28 July 2018

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Enhanced potency of human Sonic hedgehog by hydrophobic modification.

28 July 2018

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28 July 2018

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Linking colorectal cancer to Wnt signaling

28 July 2018

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

28 July 2018

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Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

28 July 2018

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Basal cell carcinomas in mice overexpressing Gli2 in skin

28 July 2018

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Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

28 July 2018

1 reference

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Sonic hedgehog opposes epithelial cell cycle arrest

28 July 2018

1 reference

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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

28 July 2018

1 reference

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Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

28 July 2018

1 reference

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Activating Smoothened mutations in sporadic basal-cell carcinoma

28 July 2018

1 reference

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Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

28 July 2018

1 reference

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Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

28 July 2018

1 reference

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Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

28 July 2018

1 reference

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Basal cell carcinomas in mice overexpressing sonic hedgehog

28 July 2018

1 reference

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Sporadic medulloblastomas contain PTCH mutations.

28 July 2018

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Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

28 July 2018

1 reference

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

28 July 2018

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Sertoli cell signaling by Desert hedgehog regulates the male germline

28 July 2018

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Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

28 July 2018

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Human homolog of patched, a candidate gene for the basal cell nevus syndrome

28 July 2018

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Relationship between sunlight exposure and a key genetic alteration in basal cell carcinoma

28 July 2018

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Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele.

28 July 2018

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Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

28 July 2018

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28 July 2018

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Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin

28 July 2018

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The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

28 July 2018

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Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

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Teratogen-mediated inhibition of target tissue response to Shh signaling

21 January 2018

1 reference

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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

1 reference

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The Hedgehog signalling pathway and cancer

21 January 2018

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Nonmelanoma skin cancer in the United States: incidence.

21 January 2018

1 reference

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29 October 2018

Identifiers

DOI

10.1073/PNAS.0732813100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12679522 AND SRC:MED&resulttype=core&format=json

2 November 2019

0 references

1 reference

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2 November 2019

PubMed publication ID

12679522

1 reference