Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients (Q33964050)

30 July 2017

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title

Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients (English)

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30 July 2017

Anders Asberg

1

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30 July 2017

publication date

1 January 2003

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30 July 2017

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30 July 2017

volume

63

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30 July 2017

issue

4

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30 July 2017

page(s)

367-378

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Bilateral pharmacokinetic interaction between cyclosporine A and atorvastatin in renal transplant recipients

30 July 2017

cites work

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12 December 2020

Rational assessment of the interaction profile of cerivastatin supports its low propensity for drug interactions

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12 December 2020

Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses*

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12 December 2020

Rhabdomyolysis and HMG-CoA reductase inhibitors

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12 December 2020

Clinical pharmacokinetics of fibric acid derivatives (fibrates).

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12 December 2020

A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters

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12 December 2020

Cholesterol-lowering therapy after heart transplantation: a 12-month randomized trial

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12 December 2020

A double-blind placebo controlled trial of simvastatin for the treatment of dyslipidaemia in renal allograft recipients

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12 December 2020

The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions

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12 December 2020

Effect of orlistat on blood cyclosporin concentration in an obese heart transplant patient

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12 December 2020

Low-dose simvastatin is a well-tolerated and efficacious cholesterol-lowering agent in ciclosporin-treated kidney transplant recipients: double-blind, randomized, placebo-controlled study in 40 patients

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12 December 2020

Orlistat decreases the plasma level of cyclosporine and may be responsible for the development of acute rejection episodes

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12 December 2020

The role of lipid lowering in transplantation.

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12 December 2020

Assessing cardiovascular risk profile of immunosuppressive agents

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12 December 2020

HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies

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12 December 2020

Plasma concentration profiles of simvastatin 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin

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12 December 2020

Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion

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12 December 2020

Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar?

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12 December 2020

Decrease in oral bioavailability of cyclosporin A by coadministration of probucol in rats.

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12 December 2020

Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A.

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12 December 2020

Effects of simvastatin in hyperlipidemic renal transplant patients receiving cyclosporine

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12 December 2020

Interaction between lovastatin and cyclosporine A after heart and kidney transplantation

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12 December 2020

Clinical efficacy and pharmacokinetics of HMG-CoA reductase inhibitors in heart transplant patients treated with cyclosporin A

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12 December 2020

Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects

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12 December 2020

Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter

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12 December 2020

Clinical pharmacokinetics of fluvastatin

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12 December 2020

Does cholestyramine interfere with cyclosporine absorption? A prospective study in renal transplant patients.

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12 December 2020

Fluvastatin in renal transplantation

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12 December 2020

Efficacy and Pharmacokinetics of Simvastatin in Heart Transplant Recipients

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12 December 2020

Cholestasis and regulation of genes related to drug metabolism and biliary transport in rat liver following treatment with cyclosporine A and sirolimus (Rapamycin).

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12 December 2020

Beneficial effects of atorvastatin in the treatment of hyperlipidemia after renal transplantation

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12 December 2020

Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients

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12 December 2020

In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s

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12 December 2020

Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

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12 December 2020

Pharmacokinetic evaluation of the possible interaction between selected concomitant medications and orlistat at steady state in healthy subjects

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12 December 2020

Effect of simvastatin on cyclosporine unbound fraction and apparent blood clearance in heart transplant recipients

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12 December 2020

The effects of dietary supplementation with fish oil on renal function and the course of early postoperative rejection episodes in cyclosporine-treated renal transplant recipients

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12 December 2020

Lack of effect of gemfibrozil on cyclosporine blood concentrations in kidney-transplanted patients

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12 December 2020

Long-term survival in renal transplant recipients with graft function

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12 December 2020

The long-term effects of the lipid-lowering agent fenofibrate in hyperlipidemic heart transplant recipients.

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12 December 2020

Efficacy and muscle safety of fluvastatin in cyclosporine-treated cardiac and renal transplant recipients: an exercise provocation test

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12 December 2020

Effect of pravastatin in the treatment of hypercholesterolemia after renal transplantation under cyclosporine and prednisone

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12 December 2020

Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients

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12 December 2020

Fluvastatin and low-density lipoprotein oxidation in hypercholesterolemic renal transplant patients

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12 December 2020

Atorvastatin: a hydroxymethylglutaryl-coenzyme A reductase inhibitor

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12 December 2020

Reduction in blood cyclosporine concentration by orlistat in two renal transplant patients

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12 December 2020

Cyclosporine pharmacokinetics and variability from a microemulsion formulation--a multicenter investigation in kidney transplant patients

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12 December 2020

Pharmacokinetics and pharmacodynamics of fluvastatin in heart transplant recipients taking cyclosporine A.

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12 December 2020

FDA adverse event reports on statin-associated rhabdomyolysis

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12 December 2020

Small intestinal metabolism of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor lovastatin and comparison with pravastatin

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12 December 2020

The effect of food and cholestyramine on the absorption of cyclosporine in cardiac transplant recipients.

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12 December 2020

Drugs for treatment of patients with high cholesterol blood levels and other dyslipidemias.

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12 December 2020

Interaction between probucol and cyclosporine in renal transplant patients

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12 December 2020

Effect of probucol on the concentration of cyclosporin A in patients with nephrotic syndrome

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12 December 2020

Pharmacokinetics of cyclosporine in hyperlipidaemic long-term survivors of heart transplantation. Lack of interaction with the lipid-lowering agent, fenofibrate

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12 December 2020

Factors influencing cyclosporine blood concentration-dose ratio

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12 December 2020

Evaluation of fluvastatin in the treatment of hypercholesterolemia in renal transplant recipients taking cyclosporine

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12 December 2020

Obesity in transplant patients: case report showing interference of orlistat with absorption of cyclosporine and review of literature

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12 December 2020

Decreased cyclosporine levels during gemfibrozil treatment of hyperlipidemia after kidney transplantation

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12 December 2020

Effect of dietary fish oil on renal function and rejection in cyclosporine-treated recipients of renal transplants

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12 December 2020

The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein

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12 December 2020

Effect of fluvastatin for safely loweringatherogenic lipids in renal transplant patients receiving cyclosporine

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12 December 2020

Safety and efficacy of low dose simvastatin in cardiac transplant recipients treated with cyclosporine

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12 December 2020

Dietary supplementation with fish oil modifies renal reserve filtration capacity in postoperative, cyclosporin A-treated renal transplant recipients

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12 December 2020

Effects of simvastatin and pravastatin on hyperlipidemia and cyclosporin blood levels in renal transplant recipients

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12 December 2020

HMG-CoA reductase inhibitors and P-glycoprotein modulation

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12 December 2020

The effects of orlistat on weight and on serum lipids in obese patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled, multicentre study

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12 December 2020

Co-administration of orlistat and cyclosporine in a heart transplant recipient

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12 December 2020

Low-dose simvastatin is safe in hyperlipidaemic renal transplant patients

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12 December 2020

The interaction of fluvastatin and cyclosporin A in renal transplant patients

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12 December 2020

Low-dose lovastatin in hyperlipidemic kidney graft recipients with cyclosporine A

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12 December 2020

10.2165/00003495-200363040-00003

Identifiers

DOI

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Dimensions Publication ID

30 July 2017

1047740919

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