Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo. (Q33960458)

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English	Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.	scientific article

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15 March 2020

Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo (English)

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15 March 2020

pulmonary fibrosis

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arsenic trioxide

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5

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15 March 2020

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15 March 2020

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Fayong Luo

1

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15 March 2020

Yan Zhuang

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15 March 2020

Mark D Sides

3

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15 March 2020

Cecilia G Sanchez

4

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15 March 2020

Joseph A Lasky

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15 March 2020

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24 April 2014

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15 March 2020

Respiratory Research

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15 March 2020

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15 March 2020

51

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15 March 2020

describes a project that uses

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11 June 2022

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Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Arsenic trioxide for management of acute promyelocytic leukemia: current evidence on its role in front-line therapy and recurrent disease

1 reference

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5 July 2018

Inhibition of arsenic induced-rat liver injury by grape seed exact through suppression of NADPH oxidase and TGF-β/Smad activation

1 reference

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5 July 2018

Arsenic alters ATP-dependent Ca² signaling in human airway epithelial cell wound response.

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5 July 2018

Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice

1 reference

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5 July 2018

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

PML-IV functions as a negative regulator of telomerase by interacting with TERT

1 reference

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5 July 2018

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Acute promyelocytic leukemia: from highly fatal to highly curable

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Murine models of pulmonary fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

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5 July 2018

The myofibroblast: one function, multiple origins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Incidence and prevalence of idiopathic pulmonary fibrosis

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5 July 2018

Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction.

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5 July 2018

Cytoplasmic PML function in TGF-beta signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

PML is a direct p53 target that modulates p53 effector functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

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5 July 2018

Body language: the function of PML nuclear bodies in apoptosis regulation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113202

5 July 2018

Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression

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5 July 2018

Dual effects of arsenic trioxide (As2O3) on non-acute promyelocytic leukaemia myeloid cell lines: induction of apoptosis and inhibition of proliferation.

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5 July 2018

Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission

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History of the development of arsenic derivatives in cancer therapy

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5 July 2018

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

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5 July 2018

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

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5 July 2018

Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality

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21 January 2018

Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation.

1 reference

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21 January 2018

Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome

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21 January 2018

Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.

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29 October 2018

Reactive oxygen species-mediated killing of activated fibroblasts by arsenic trioxide ameliorates fibrosis in a murine model of systemic sclerosis

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The Role of Strain Variation in Murine Bleomycin-lnduced Pulmonary Fibrosis1,2

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Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts

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https://pubmed.ncbi.nlm.nih.gov/24762191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1465-9921-15-51

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15 March 2020

Dimensions Publication ID

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https://scigraph.springernature.com/pub.10.1186/1465-9921-15-51

9 September 2019

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15 March 2020

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15 March 2020

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