Mechanisms of action of methotrexate. (Q33957205)

30 July 2017

1 reference

title

Mechanisms of action of methotrexate. (English)

1 reference

30 July 2017

1 reference

Genestier L

1

1 reference

30 July 2017

Paillot R

2

1 reference

30 July 2017

Quemeneur L

3

1 reference

30 July 2017

Izeradjene K

4

1 reference

30 July 2017

Revillard JP

5

1 reference

30 July 2017

publication date

1 May 2000

1 reference

30 July 2017

1 reference

30 July 2017

volume

47

1 reference

30 July 2017

issue

2-3

1 reference

30 July 2017

page(s)

247-257

1 reference

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Leukocyte adherence in rat mesenteric venules: effects of adenosine and methotrexate

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Polyglutamation of methotrexate. Is methotrexate a prodrug?

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Cyclosporine, methotrexate, and prednisone compared with cyclosporine and prednisone for prophylaxis of acute graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Adenosine, an endogenous anti-inflammatory agent

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Apoptosis as a mechanism of cell death induced by different chemotherapeutic drugs in human leukemic T-lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Cyclosporin A and methotrexate in canine marrow transplantation: engraftment, graft-versus-host disease, and induction of intolerance

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Advances in chemotherapy of cancer in man

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Mechanisms of methotrexate action in rheumatoid arthritis. Selective decrease in synovial collagenase gene expression

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Apoptosis without decrease of cell DNA content

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

The cellular pharmacology of methotrexate

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Increased adenosine concentration in blood from ischemic myocardium by AICA riboside. Effects on flow, granulocytes, and injury

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate induces apoptotic cell death in human keratinocytes

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Folate-binding proteins

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Studies with a mathematical model of folate metabolism

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Programmed cell death and extrathymic reduction of Vβ8 CD4 T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate as an adjunct in the treatment of persistent mild cardiac allograft rejection

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

The effect of cytotoxic drugs on graft-versus-host disease in mice.

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Activation-dependent lymphocyte apoptosis induced by methotrexate

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Characterization of the methotrexate transport pathway in murine L1210 leukemia cells: involvement of a membrane receptor and a cytosolic protein

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Inhibition by adenosine of reactive oxygen metabolite production by human polymorphonuclear leucocytes

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Influence of lipophilicity and carboxyl group content on the rate of hydroxylation of methotrexate derivatives by aldehyde oxidase

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate: mechanism of action in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Rapid Development of Resistance to Antifolates In Vitro: Possible Clinical Implication

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Methotrexate regimens for control of graft-versus-host disease in dogs with allogeneic marrow grafts

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Graft-versus-host disease as adoptive immunotherapy in patients with advanced hematologic neoplasms

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Human thymidylate synthetase--III. Effects of methotrexate and folate analogs

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Studies of the metabolism of methotrexate by intestinal flora. I. Identification and study of biological properties of the metabolite 4-amino-4-deoxy-N 10 -methylpteroic acid

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Efficacy of low-dose methotrexate in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

Comparison of low-dose oral pulse methotrexate and placebo in the treatment of rheumatoid arthritis. A controlled clinical trial

1 reference

https://api.crossref.org/works/10.1016/S0162-3109(00)00189-2

7 January 2021

10.1016/S0162-3109(00)00189-2

Identifiers

DOI

1 reference

release_ju6qpyqupbg43cfvxpj7lpplcq

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ju6qpyqupbg43cfvxpj7lpplcq

24 November 2022

mapped directly with Wikidata item

1 reference