Discovery research: the scientific challenge of finding new antibiotics (Q33941796)

30 July 2017

title

Discovery research: the scientific challenge of finding new antibiotics (English)

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ORCID Public Data File 2021

30 July 2017

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author name string

David M Livermore

series ordinal

1

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30 July 2017

British Society for Antimicrobial Chemotherapy Working Party on The Urgent Need: Regenerating Antibacterial Drug Discovery and Development

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

23 June 2011

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Journal of Antimicrobial Chemotherapy

30 July 2017

published in

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30 July 2017

volume

66

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30 July 2017

issue

9

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30 July 2017

page(s)

1941-1944

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Why is big Pharma getting out of antibacterial drug discovery?

30 July 2017

cites work

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Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-Producing Enterobacteriaceae

21 January 2018

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

21 January 2018

1 reference

Challenges of antibacterial discovery

21 January 2018

1 reference

Mechanisms of resistance to quinolones

21 January 2018

1 reference

Alarming β-lactamase-mediated resistance in multidrug-resistant Enterobacteriaceae

21 January 2018

1 reference

Distribution of 16S rRNA methylases among different species of Gram-negative bacilli with high-level resistance to aminoglycosides

21 January 2018

1 reference

Mechanisms of RND multidrug efflux pumps

21 January 2018

1 reference

Discovery of a novel and potent class of FabI-directed antibacterial agents

21 January 2018

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Drug-like properties and the causes of poor solubility and poor permeability

21 January 2018

1 reference

Type IIA topoisomerase inhibition by a new class of antibacterial agents

21 January 2018

1 reference

Three decades of beta-lactamase inhibitors

21 January 2018

1 reference

In vitro potentiation of carbapenems with ME1071, a novel metallo-beta-lactamase inhibitor, against metallo-beta-lactamase- producing Pseudomonas aeruginosa clinical isolates

21 January 2018

1 reference

Practical applications and feasibility of efflux pump inhibitors in the clinic--a vision for applied use.

21 January 2018

1 reference

8-Azatetracyclines: Synthesis and Evaluation of a Novel Class of Tetracycline Antibacterial Agents

21 January 2018

1 reference

Polymyxins and their novel derivatives

21 January 2018

1 reference

Medicinal plants and antimicrobial activity

21 January 2018

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A guide to successful bioprospecting: informed by actinobacterial systematics

21 January 2018

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A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus

21 January 2018

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Molecular engineering approaches to peptide, polyketide and other antibiotics

21 January 2018

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Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

21 January 2018

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Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

21 January 2018

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A Wellcome experiment in seeding drug discovery

21 January 2018

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Synthesis and spectrum of the neoglycoside ACHN-490

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1093/JAC/DKR262

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30 July 2017

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