New insight into the mechanisms underlying Th2 cell development and susceptibility to Leishmania major in BALB/c mice (Q33939868)

30 July 2017

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title

New insight into the mechanisms underlying Th2 cell development and susceptibility to Leishmania major in BALB/c mice (English)

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30 July 2017

Leishmania major

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Fabienne Tacchini-Cottier

inferred from title

author

object named as

F Tacchini-Cottier

3

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author name string

P Launois

1

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30 July 2017

H Himmelrich

2

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30 July 2017

G Milon

4

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30 July 2017

J A Louis

5

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30 July 2017

publication date

1 January 1999

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30 July 2017

published in

Microbes and Infection

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30 July 2017

volume

1

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30 July 2017

issue

1

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30 July 2017

page(s)

59-64

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Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development

30 July 2017

cites work

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Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

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Recombinant interleukin 12 cures mice infected with Leishmania major

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Pathogen-induced Th1 phenotype development in CD4 αβ-TCR transgenic T cells is macrophage dependent

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T cell genetic background determines default T helper phenotype development in vitro

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7 January 2021

Resistance to Leishmania major induced by tolerance to a single antigen

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7 January 2021

IL-4 Rapidly Produced by Vβ4 Vα8 CD4 T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

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7 January 2021

In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4 T cells which are NK1.1-

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Dendritic cells and macrophages are required for Th1 development of CD4 T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependent

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Resistance and abrogation of resistance to cutaneous leishmaniasis in reconstituted BALB/c nude mice

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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Interleukin 12 acts directly on CD4 T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

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7 January 2021

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4 T cells from T cell receptor transgenic mice

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7 January 2021

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response

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7 January 2021

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7 January 2021

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling

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7 January 2021

Role of NK1.1 T cells in a TH2 response and in immunoglobulin E production

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7 January 2021

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

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Identifiers

DOI

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30 July 2017

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