Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine (Q33927093)

30 July 2017

title

Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine (English)

1 reference

30 July 2017

main subject

regenerative medicine

1 reference

Jiangbo Wang

1

1 reference

30 July 2017

Jiuyi Lu

2

1 reference

30 July 2017

Michael C Bond

3

1 reference

30 July 2017

Minyong Chen

4

1 reference

30 July 2017

Xiu-Rong Ren

5

1 reference

30 July 2017

H Kim Lyerly

6

1 reference

30 July 2017

Larry S Barak

7

1 reference

30 July 2017

Wei Chen

8

1 reference

30 July 2017

language of work or name

English

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publication date

3 May 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

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30 July 2017

volume

107

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30 July 2017

issue

20

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30 July 2017

page(s)

9323-9328

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Evidence for allosteric interactions of antagonist binding to the smoothened receptor

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Chemoattractive activity of sonic hedgehog in the adult subventricular zone modulates the number of neural precursors reaching the olfactory bulb.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Acute neonatal glucocorticoid exposure produces selective and rapid cerebellar neural progenitor cell apoptotic death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

A chemical approach to stem-cell biology and regenerative medicine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Purmorphamine activates the Hedgehog pathway by targeting Smoothened.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Cerebellar granule cell precursors can differentiate into astroglial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Small molecule modulation of Smoothened activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Hedgehog signaling in animal development: paradigms and principles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Stress and hippocampal neurogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Sonic hedgehog regulates the growth and patterning of the cerebellum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0910712107

Endogenous stem cell proliferation induced by intravenous hedgehog agonist administration after contusion in the adult rat spinal cord

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0910712107

Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0910712107

Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2889058

Sonic hedgehog promotes stem-cell potential of Müller glia in the mammalian retina

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439738

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regenerative medicine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439738

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0910712107

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference