Brain ischemia and reperfusion: molecular mechanisms of neuronal injury (Q33923323)

30 July 2017

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title

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury (English)

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30 July 2017

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White BC

1

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30 July 2017

Sullivan JM

2

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30 July 2017

DeGracia DJ

3

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30 July 2017

O'Neil BJ

4

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30 July 2017

Neumar RW

5

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30 July 2017

Grossman LI

6

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30 July 2017

Rafols JA

7

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30 July 2017

Krause GS

8

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30 July 2017

publication date

1 October 2000

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Journal of the Neurological Sciences

30 July 2017

published in

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30 July 2017

volume

179

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30 July 2017

issue

S 1-2

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30 July 2017

page(s)

1-33

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Ischemia, resuscitation, and reperfusion: mechanisms of tissue injury and prospects for protection

30 July 2017

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Selfotel in acute ischemic stroke : possible neurotoxic effects of an NMDA antagonist

7 January 2021

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Brain cell death following ischemia and reperfusion

7 January 2021

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Cerebral energy reserves after prolonged hypoxia and ischemia

7 January 2021

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The role of postischemic recirculation in the development of ischemic neuronal injury following complete cerebral ischemia

7 January 2021

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Ultrastructural and ionic studies in global ischemic dog brain.

7 January 2021

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Histological changes of neuronal damage in vegetative dogs induced by 18 minutes of complete global brain ischemia: two-phase damage of Purkinje cells and hippocampal CA1 pyramidal cells

7 January 2021

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Protective effects of combined superoxide dismutase and deferoxamine on recovery of cerebral blood flow and function after cardiac arrest in dogs

7 January 2021

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Attenuation of postischemic cerebral hypoperfusion by the 21-aminosteroid U74006F

7 January 2021

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Reversibility of ischemic brain damage

7 January 2021

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Cerebral blood flow, glucose utilization, regional glucose, and ATP content during the maturation period of delayed ischemic injury in gerbil brain

7 January 2021

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Prolonged cardiac arrest and resuscitation in dogs: brain mitochondrial function with different artificial perfusion methods

7 January 2021

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The effect of ischaemia and recirculation on protein synthesis in the rat brain

7 January 2021

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Regional protein synthesis in rat brain following acute hemispheric ischemia

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Activation of the glutamate metabotropic receptor protects retina against N-methyl-D-aspartate toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

In rats, the metabotropic glutamate receptor-triggered hippocampal neuronal damage is strain-dependent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Relationships between ions and energy metabolism: cerebral calcium movements during ischaemia and subsequent recovery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Reductions of ?-Aminobutyric Acid and Glutamate Uptake and (Na K )-ATPase Activity in Brain Slices and Synaptosomes by Arachidonic Acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Lipid peroxidation-induced inhibition of gamma-aminobutyric acid uptake in rat brain synaptosomes: protection by glucocorticoids

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Earliest irreversible changes during ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Mechanism of arachidonic acid liberation during ischemia in gerbil cerebral cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Structure of porcine pancreatic prephospholipase A2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Regulation of endogenous calcium-dependent synaptic membrane phospholipase A2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Brain cortical fatty acids and phospholipids during and following complete and severe incomplete ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Biphasic liberation of arachidonic and stearic acids during cerebral ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effect of transient ischemia on free fatty acids and phospholipids in the gerbil brain. Lipid peroxidation as a possible cause of postischemic injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Arachidonic acid as a neurotoxic and neurotrophic substance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Immunohistochemical localization of glutathione peroxidase in the brain of the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Natural course of iron delocalization and lipid peroxidation during the first eight hours following a 15-minute cardiac arrest in dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Regional lipid peroxidation in rat brain in vitro: possible role of endogenous iron

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Oxygen toxicity, oxygen radicals, transition metals and disease

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Role of metals in oxygen radical reactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Trace elements in human brain: copper, zinc, iron, and magnesium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Nitric oxide synthase in models of focal ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Immunohistochemical detection of nitrotyrosine in postischemic cerebral cortex in gerbil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Potentiation of lipid peroxides by ischemia in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Lipid peroxidation in vivo induced by reversible global ischemia in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Relationship between free radical production and lipid peroxidation during ischemia-reperfusion injury in the rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Prevention of post-ischemic brain lipid conjugated diene production and neurological injury by hydroxyethyl starch-conjugated deferoxamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effect on biochemical markers of brain injury of therapy with deferoxamine or superoxide dismutase following cardiac arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Fluorescent histochemical localization of lipid peroxidation during brain reperfusion following cardiac arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Immunocytochemical method for investigating in vivo neuronal oxygen radical-induced lipid peroxidation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Postischemic accumulation of lipid peroxidation products in the rat brain: immunohistochemical detection of 4-hydroxy-2-nonenal modified proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Lipid transport pathways in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Ischemia-induced changes in cerebral mitochondrial free fatty acids, phospholipids, and respiration in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Mechanisms of lipid peroxidation in erythrocytes of vitamin E-deficient rats and in phospholipid model systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The influence of phospholipase A2 and glutathione peroxidase on the elimination of membrane lipid peroxides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Stimulation of phospholipase A2 activity by oxygen-derived free radicals in isolated brain capillaries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Phospholipid degradation and cellular edema induced by free radicals in brain cortical slices

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Lipid hydroperoxides inhibit reacylation of phospholipids in neuronal membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Cell death, calcium mobilization, and immunostaining for phosphorylated eukaryotic initiation factor 2-alpha (eIF2alpha) in neuronally differentiated NB-104 cells: arachidonate and radical-mediated injury mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

A quantitative morphological assessment of the effect of lidoflazine and deferoxamine therapy on global brain ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effect of the aminosteroid U74006F after cardiopulmonary arrest in dogs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effects of U74006F on multifocal cerebral blood flow and metabolism after cardiac arrest in dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The effect of EMHP on post-cardiac arrest survival of rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

DNA replication initiation, doubling of rate of phospholipid synthesis, and cell division in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Regulatory interactions between phospholipid synthesis and DNA replication in Caulobacter crescentus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Ultrastructural consequences of radical damage before and after differentiation of neuroblastoma B-104 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Calcium-activated neutral protease (calpain) system: structure, function, and regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Is calpain activity regulated by membranes and autolysis or by calcium and calpastatin?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Distribution of calpain I, an enzyme associated with degenerative activity, in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Distribution of calpains I and II in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Immunohistochemical distribution of calcium-activated neutral proteinases and endogenous CANP inhibitor in the rabbit hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Distribution of calcium-activated neutral protease inhibitor in the central nervous system of the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Calpain inhibitors block Ca(2 )-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Inhibition of proteolysis protects hippocampal neurons from ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Spectrin proteolysis in the hippocampus: a biochemical marker for neuronal injury and neuroprotection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Calpain activation in apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Modulation of cellular signals by calpain

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Activation of intracellular calcium-activated neutral proteinase in erythrocytes and its inhibition by exogenously added inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Procalpain is activated on the plasma membrane and the calpain acts on the membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Brain mu-calpain autolysis during global cerebral ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Implication of calpain in caspase activation during B cell clonal deletion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Protein synthesis in the cat brain after prolonged cerebral ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Changes in brain energy metabolism and protein synthesis following transient bilateral ischemia in the gerbil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Cerebral protein synthesis and ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Recovery of monkey brain after prolonged ischemia. II. Protein synthesis and morphological alterations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Persistent inhibition of protein synthesis precedes delayed neuronal death in postischemic gerbil hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effects of a new calcium channel blocker, KB-2796, on protein synthesis of the CA1 pyramidal cell and delayed neuronal death following transient forebrain ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Regional impairment of protein synthesis following brief cerebral ischemia in the gerbil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

[14C]leucine incorporation into brain proteins in gerbils after transient ischemia: relationship to selective vulnerability of hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Temporal profile of neuronal damage in a model of transient forebrain ischemia

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Recovery of protein synthesis in tolerance-induced hippocampal CA1 neurons after transient forebrain ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Thymine glycols and pyrimidine dimers in brain DNA during post-ischemic reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Brain nuclear DNA survives cardiac arrest and reperfusion

7 January 2021

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https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Brain mitochondrial DNA is not damaged by prolonged cardiac arrest or reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Determination of RNA content in postischemic gerbil brain by in situ hybridization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Nuclear-envelope nucleoside triphosphatase kinetics and mRNA transport following brain ischemia and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Assessment of free radical-induced damage in brain proteins after ischemia and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Role of ribonuclease action in phenylalanine-induced disaggregation of rat cerebral polyribosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Studies of the protein synthesis system in the brain cortex during global ischemia and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

An in vitro amino acid incorporation method for assessing the status of in vivo protein synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

In vitro ischemia and protein synthesis in the rat hippocampal slice: the role of calcium and NMDA receptor activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Purification of a novel heat-stable translational inhibitor from rabbit reticulocyte lysates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Purification and characterization of guanine nucleotide-exchange factor, eIF-2B, and p37 calmodulin-binding protein from calf brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Translational initiation factor eIF-2 subcellular levels and phosphorylation status in the developing rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Role of mRNA competition in regulating translation: further characterization of mRNA discriminatory initiation factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Differential effect of insulin and epidermal growth factor on the mRNA translocation system and transport of specific poly(A ) mRNA and poly(A-) mRNA in isolated nuclei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Platelet-derived growth factor stimulates phosphorylation of the 25 kDa mRNA cap binding protein (eIF-4E) in human lung fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Phosphorylation of translation initiation factor eIF-4E is induced in a ras-dependent manner during nerve growth factor-mediated PC12 cell differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Calpain mediates eukaryotic initiation factor 4G degradation during global brain ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effect of Brain Ischemia and Reperfusion on the Localization of Phosphorylated Eukaryotic Initiation Factor 2α

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Ultrastructural localization of phosphorylated eIF2alpha [eIF2alpha(P)] in rat dorsal hippocampus during reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin induces dephosphorylation of eukaryotic initiation factor 2alpha and restores protein synthesis in vulnerable hippocampal neurons after transient brain ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Heat shock RNA levels in brain and other tissues after hyperthermia and transient ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Internal initiation of translation directed by the 5'-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Initiation of Apaf-1 translation by internal ribosome entry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Translation of CUG- but not AUG-initiated forms of human fibroblast growth factor 2 is activated in transformed and stressed cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Reduction of delayed neuronal death by inhibition of protein synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

7 January 2021

1 reference

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Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology To yeast GCN2 protein kinase

7 January 2021

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Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]

7 January 2021

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Geldanamycin provides posttreatment protection against glutamate-induced oxidative toxicity in a mouse hippocampal cell line

7 January 2021

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Hypoxia and ischemia modifies histamine metabolism and transport in brain synaptosomes

7 January 2021

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Translation of the yeast transcriptional activator GCN4 is stimulated by purine limitation: implications for activation of the protein kinase GCN2.

7 January 2021

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Restoring adenine nucleotides in a brain slice model of cerebral reperfusion

7 January 2021

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Mechanism of activation of the heme-stabilized translational inhibitor of reticulocyte lysates by calcium ions and phospholipid

7 January 2021

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Tissue distribution and immunoreactivity of heme-regulated eIF-2 alpha kinase determined by monoclonal antibodies

7 January 2021

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Expression of p68 protein kinase as recognized by the monoclonal antibody TJ4C4 during human fetal development

7 January 2021

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Proteins that interact with PKR.

7 January 2021

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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

7 January 2021

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Activation of the apoptotic Fas antigen-encoding gene upon influenza virus infection involving spontaneously produced beta-interferon

7 January 2021

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Localization of Epstein-Barr virus-encoded RNAs EBER-1 and EBER-2 in interphase and mitotic Burkitt lymphoma cells

7 January 2021

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Nuclear localization of the interferon-inducible protein kinase PKR in human cells and transfected mouse cells

7 January 2021

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Eukaryotic initiation factor 2alpha kinase and phosphatase activity during postischemic brain reperfusion

7 January 2021

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

7 January 2021

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Mechanism of inhibition of polypeptide chain initiation in calcium-depleted Ehrlich ascites tumor cells

7 January 2021

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Reversible phosphorylation of eukaryotic initiation factor 2 alpha in response to endoplasmic reticular signaling

7 January 2021

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The structure and regulation of protein phosphatases

7 January 2021

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The protein phosphatases involved in cellular regulation. 1. Classification and substrate specificities.

7 January 2021

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Activity of protein phosphatases against initiation factor-2 and elongation factor-2.

7 January 2021

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Effects of skeletal muscle protein phosphatase inhibitor-2 on protein synthesis and protein phosphorylation in rabbit reticulocyte lysates

7 January 2021

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Tissue distribution of isoforms of type-1 protein phosphatase PP1 in mouse tissues and its diabetic alterations.

7 January 2021

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The alpha and gamma 1 isoforms of protein phosphatase 1 are highly and specifically concentrated in dendritic spines

7 January 2021

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Differential expression of protein phosphatase 1 isoforms in mammalian brain.

7 January 2021

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Phosphorylase phosphatase: new horizons for an old enzyme

7 January 2021

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The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

7 January 2021

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On target with a new mechanism for the regulation of protein phosphorylation

7 January 2021

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Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation

7 January 2021

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Protein phosphatase 2A inhibitors, I(1)(PP2A) and I(2)(PP2A), associate with and modify the substrate specificity of protein phosphatase 1

7 January 2021

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Physiologic importance of protein phosphatase inhibitors

7 January 2021

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Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle

7 January 2021

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The hormonal control of glycogen metabolism: dephosphorylation of protein phosphatase inhibitor-1 in vivo in response to insulin

7 January 2021

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Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells

7 January 2021

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Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.

7 January 2021

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Immunolocalisation of protein phosphatase inhibitor-1 in the cerebral cortex of the rat, cat and ferret

7 January 2021

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Insulin attenuates ischemic brain damage independent of its hypoglycemic effect.

7 January 2021

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Roles of a 67-kDa polypeptide in reversal of protein synthesis inhibition in heme-deficient reticulocyte lysate

7 January 2021

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Regulation of eIF-2 alpha-subunit phosphorylation in reticulocyte lysate

7 January 2021

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A eukaryotic translation initiation factor 2-associated 67 kDa glycoprotein partially reverses protein synthesis inhibition by activated double-stranded RNA-dependent protein kinase in intact cells

7 January 2021

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Viral infection. II. Hemin induces overexpression of p67 as it partially prevents appearance of an active p67-deglycosylase in baculovirus-infected insect cells

7 January 2021

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Viral infection. I. Regulation of protein synthesis during vaccinia viral infection of animal cells

7 January 2021

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Ribosomal protein L7/L12 is required for optimal translation

7 January 2021

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Dynamics of regional brain metabolism and gene expression after middle cerebral artery occlusion in mice

7 January 2021

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Apoptosis: molecular regulation of cell death

7 January 2021

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7 January 2021

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Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways

7 January 2021

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FLICE Induced Apoptosis in a Cell-free System

7 January 2021

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Target protease specificity of the viral serpin CrmA. Analysis of five caspases

7 January 2021

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Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

7 January 2021

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Apoptosis in the heart: when and why?

7 January 2021

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Fas antigen mRNA induction in postischemic murine brain

7 January 2021

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FK506 prevents stroke-induced generation of ceramide and apoptosis signaling

7 January 2021

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Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

7 January 2021

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Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

7 January 2021

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Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB.

7 January 2021

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Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2

7 January 2021

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

7 January 2021

1 reference

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

7 January 2021

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Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

7 January 2021

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The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

7 January 2021

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Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus.

7 January 2021

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Adenosine prevents activation of transcription factor NF-kappa B and enhances activator protein-1 binding activity in ischemic rat heart

7 January 2021

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Global cerebral ischemia activates nuclear factor-κB prior to evidence of DNA fragmentation

7 January 2021

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Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-kappaB in rats

7 January 2021

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Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity.

7 January 2021

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Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

7 January 2021

1 reference

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Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.

7 January 2021

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CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9.

7 January 2021

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Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

7 January 2021

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

7 January 2021

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Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

7 January 2021

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Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats.

7 January 2021

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Release of cytochrome c from mitochondria to cytosol in gerbil hippocampal CA1 neurons after transient forebrain ischemia

7 January 2021

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Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition.

7 January 2021

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Cellular survival: a play in three Akts

7 January 2021

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Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis

7 January 2021

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Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases.

7 January 2021

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Characterization of seven murine caspase family members

7 January 2021

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Detection of DNA breaks in apoptotic cells utilizing the DNA binding domain of poly(ADP-ribose) polymerase with fluorescence microscopy

7 January 2021

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Complete inhibition of poly(ADP-ribose) polymerase activity prevents the recovery of C3H10T1/2 cells from oxidative stress

7 January 2021

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Actin cleavage by CPP-32/apopain during the development of apoptosis

7 January 2021

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

7 January 2021

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Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons.

7 January 2021

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Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

7 January 2021

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Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

7 January 2021

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Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells

7 January 2021

1 reference

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Dissecting processing and apoptotic activity of a cysteine protease by mutant analysis

7 January 2021

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Cleavage of Poly(ADP-ribose) Polymerase by Interleukin-1β Converting Enzyme and Its Homologs TX and Nedd-2

7 January 2021

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Bcl-2 expression in neural cells blocks activation of ICE/CED-3 family proteases during apoptosis.

7 January 2021

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Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death

7 January 2021

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Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2 fluxes

7 January 2021

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Inhibition of Bax channel-forming activity by Bcl-2

7 January 2021

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Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

7 January 2021

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Apoptosis and necrosis in cerebrovascular disease

7 January 2021

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

7 January 2021

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

7 January 2021

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

7 January 2021

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Ca2 -induced apoptosis through calcineurin dephosphorylation of BAD

7 January 2021

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Phosphorylation of Eukaryotic Translation Initiation Factor 2 Mediates Apoptosis in Response to Activation of the Double-stranded RNA-dependent Protein Kinase

7 January 2021

1 reference

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Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB.

7 January 2021

1 reference

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Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil

7 January 2021

1 reference

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Differential immunohistochemical localization of inositol 1,4,5-trisphosphate- and ryanodine-sensitive Ca2 release channels in rat brain.

7 January 2021

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Modulation of ryanodine binding to the cardiac Ca2 release channel by arachidonic acid

7 January 2021

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Cellular functions of immunophilins

7 January 2021

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Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

7 January 2021

1 reference

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Characterization of an exchange reaction between soluble FKBP-12 and the FKBP.ryanodine receptor complex. Modulation by FKBP mutants deficient in peptidyl-prolyl isomerase activity.

7 January 2021

1 reference

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Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

7 January 2021

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Mode of action of tacrolimus (FK506): molecular and cellular mechanisms.

7 January 2021

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The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation

7 January 2021

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A mechanism for rotamase catalysis by the FK506 binding protein (FKBP)

7 January 2021

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Peptidylproline cis-trans-isomerases: immunophilins

7 January 2021

1 reference

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Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis

7 January 2021

1 reference

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Cyclophilin A is present in rat germ cells and is associated with spermatocyte apoptosis. Reproductive Toxicology Group

7 January 2021

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Potassium is a critical regulator of apoptotic enzymes in vitro and in vivo.

7 January 2021

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Functional differences of two forms of the inhibitor of caspase-activated DNase, ICAD-L, and ICAD-S.

7 January 2021

1 reference

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Involvement of Cyclophilin D in the Activation of A mitochondrial Pore by Ca2 and Oxidant Stress

7 January 2021

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Evidence for the Involvement of a Membrane-Associated Cyclosporin-A-Binding Protein in the Ca2 -Activated Inner Membrane Pore of Heart Mitochondria

7 January 2021

1 reference

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Sensitivity of mitochondrial peptidyl-prolyl cis-trans isomerase, pyridine nucleotide hydrolysis and Ca2 release to cyclosporine a and related compounds

7 January 2021

1 reference

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Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

7 January 2021

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Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

7 January 2021

1 reference

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Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A

7 January 2021

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Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats

7 January 2021

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p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

7 January 2021

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Drastically increased expression of MYC and FOS protooncogenes during in vitro differentiation of chronic lymphocytic leukemia cells

7 January 2021

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The regulation and function of c-fos and other immediate early genes in the nervous system

7 January 2021

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Global ischemia induces NMDA receptor-mediated c-fos expression in neurons resistant to injury in gerbil hippocampus

7 January 2021

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In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia

7 January 2021

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Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global cerebral ischemia: an in situ hybridization study

7 January 2021

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Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex

7 January 2021

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Post-ischemic and kainic acid-induced c-fos protein expression in the rat hippocampus

7 January 2021

1 reference

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Suppression of post-ischemic-induced fos protein expression by an antisense oligonucleotide to c-fos mRNA leads to increased tissue damage

7 January 2021

1 reference

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Reprogramming of gene expression in postischemic rat liver: induction of proto-oncogenes and hsp 70 gene family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Speculations on the functions of the major heat shock and glucose-regulated proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Heat shock, stress proteins, chaperones, and proteotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Heat shock proteins: the search for functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Heat shock and the heat shock proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Heat shock protects cultured neurons from glutamate toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Localization of 70 kDa stress protein mRNA induction in gerbil brain after ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Synthesis of a stress protein following transient ischemia in the gerbil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Elevated expression of proto-oncogenes accompany enhanced induction of heat-shock genes after exposure of rat embryos in utero to ionizing irradiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Induction of superoxide dismutase in Escherichia coli by heat shock

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Large changes in intracellular pH and calcium observed during heat shock are not responsible for the induction of heat shock proteins in Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Global brain ischemia and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Mechanisms regulating cell number and type in the mammalian central nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin receptors are widely distributed in the central nervous system of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Nerve growth factor receptor molecules in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Localization of nerve growth factor receptor messenger RNA and protein in the adult rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Localization of Type I Insulin-Like Growth Factor Receptor Messenger RNA in the Adult Rat Brain byin SituHybridization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Trophic actions of IGF-I, IGF-II and insulin on cholinergic and dopaminergic brain neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Distribution of insulin-like growth factor 1 (IGF-1) and 2 (IGF-2) receptors in the hippocampal formation of rats and mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Epidermal growth factor and the nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Increase in basic fibroblast growth factor-like immunoreactivity in rat brain after forebrain ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Nerve growth factor in CNS repair and regeneration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Amelioration of delayed neuronal death in the hippocampus by nerve growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Postischemic seizures and necrotizing ischemic brain damage: neuroprotective effect of postischemic diazepam and insulin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin administration protects neurologic function in cerebral ischemia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin-glycerolipid mediators and gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin rapidly increases diacylglycerol by activating de novo phosphatidic acid synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Growth factor receptor tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin signal transduction: the role of protein phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Tyrosine-specific phosphorylation of calmodulin by the insulin receptor kinase purified from human placenta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The in vitro phosphorylation of calmodulin by the insulin receptor tyrosine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Location of phosphotyrosine-containing proteins by immunocytochemistry in the rat forebrain corresponds to the distribution of the insulin receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Antiapoptotic signaling by the insulin receptor in Chinese hamster ovary cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

A Role for Nuclear Factor κB in the Antiapoptotic Function of Insulin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kappaB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Activation of c-Ha-Ras by nitric oxide modulates survival responsiveness in neuronal PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor kappaB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Insulin-like growth factor-II, phosphatidylinositol 3-kinase, nuclear factor-kappaB and inducible nitric-oxide synthase define a common myogenic signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Regulation of cell death protease caspase-9 by phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Two different signal transduction pathways are implicated in the regulation of initiation factor 2B activity in insulin-like growth factor-1-stimulated neuronal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Galanin and Epinephrine Act on Distinct Receptors to Inhibit Insulin Release by the Same Mechanisms Including an Increase in K Permeability of the B-Cell Membrane*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Regulation of insulin receptor kinase by multisite phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Phospholipid peroxidation induced by the catechol-Fe3 (Cu2 ) complex: a possible mechanism of nigrostriatal cell damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Enhancement by catechols of hydroxyl-radical formation in the presence of ferric ions and hydrogen peroxide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Dopa and dopamine cause cultured neuronal death in the presence of iron

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

Caulobacter cresentus mutant defective in membrane phospholipid synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Global brain ischemia and reperfusion: modifications in eukaryotic initiation factors associated with inhibition of translation initiation

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1016/S0022-510X(00)00386-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0022-510X(00)00386-5

1 reference

30 July 2017

1 reference