Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation (Q33922831)

30 July 2017

title

Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation (English)

1 reference

30 July 2017

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reactive oxygen species

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5

Jocelyne Caboche

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30 July 2017

Delphine Charvin

1

1 reference

30 July 2017

Peter Vanhoutte

series ordinal

2

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30 July 2017

Christiane Pagès

series ordinal

3

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30 July 2017

Emilliana Borrelli

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

15 August 2005

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

102

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30 July 2017

issue

34

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30 July 2017

page(s)

12218-12223

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

30 July 2017

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5 July 2018

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5 July 2018

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Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons.

5 July 2018

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Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

5 July 2018

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Targeting the JNK pathway for therapeutic benefit in CNS disease

5 July 2018

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Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein

5 July 2018

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Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice

5 July 2018

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5 July 2018

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Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration

5 July 2018

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5 July 2018

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Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

5 July 2018

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Neuronal cell death in Huntington's disease: a potential role for dopamine

5 July 2018

1 reference

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Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin

5 July 2018

1 reference

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Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

5 July 2018

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Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line

5 July 2018

1 reference

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Dopamine receptors: from structure to function

5 July 2018

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5 July 2018

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Dopamine Induces Apoptosis through an Oxidation-involved SAPK/JNK Activation Pathway

29 October 2018

1 reference

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

5 July 2018

1 reference

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

5 July 2018

1 reference

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

5 July 2018

1 reference

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

5 July 2018

1 reference

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Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

5 July 2018

1 reference

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Neuropathological classification of Huntington's disease

5 July 2018

1 reference

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Differential loss of striatal projection neurons in Huntington disease

5 July 2018

1 reference

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In vivo autoxidation of dopamine in guinea pig striatum increases with age.

5 July 2018

1 reference

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Factors associated with slow progression in Huntington's disease

5 July 2018

1 reference

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Covariate-dependent age-at-onset distributions for Huntington disease

5 July 2018

1 reference

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Expanded huntingtin activates the c-Jun terminal kinase/c-Jun pathway prior to aggregate formation in striatal neurons in culture.

5 July 2018

1 reference

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Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology

29 October 2018

1 reference

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C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis.

29 October 2018

1 reference

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Polyglutamine expansion induces a protein-damaging stress connecting heat shock protein 70 to the JNK pathway

29 October 2018

1 reference

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Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Dopamine D2 receptor mediated presynaptic inhibition of striatopallidal GABA(A) IPSCs in vitro

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Dopamine modulates the susceptibility of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Transgenic mice in the study of polyglutamine repeat expansion diseases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

D2 receptor-mediated inhibition of GABA release by endogenous dopamine in the rat globus pallidus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Decreases in evoked overflow of dopamine in rat striatum after neurotoxic doses of methamphetamine.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Parenterally administered 3-nitropropionic acid and amphetamine can combine to produce damage to terminals and cell bodies in the striatum

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Functional decline in Huntington's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1189314

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16103364

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0502698102

1 reference

30 July 2017

0 references

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30 July 2017

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