Novel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422. (Q33921497)

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2 February 2020

title

Novel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422 (English)

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2 February 2020

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6

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2 February 2020

author name string

Fiona Grueninger

1

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2 February 2020

Bernd Bohrmann

2

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2 February 2020

Klaus Christensen

3

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2 February 2020

Martin Graf

4

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2 February 2020

Doris Roth

5

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2 February 2020

publication date

3 June 2011

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Molecular and Cellular Biochemistry

2 February 2020

published in

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2 February 2020

volume

357

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2 February 2020

issue

1-2

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2 February 2020

page(s)

199-207

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Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

2 February 2020

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Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.

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Phosphorylated serine422 on tau proteins is a pathological epitope found in several diseases with neurofibrillary degeneration

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