Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study (Q33919261)

30 July 2017

title

Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study (English)

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blood coagulation disease

30 July 2017

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1 reference

8

Tom van der Poll

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30 July 2017

Marcel Schouten

1

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30 July 2017

Koenraad F van der Sluijs

2

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30 July 2017

Bruce Gerlitz

3

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30 July 2017

Brian W Grinnell

4

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30 July 2017

Joris J T H Roelofs

5

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30 July 2017

Marcel M Levi

6

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30 July 2017

Cornelis van 't Veer

7

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30 July 2017

publication date

14 April 2010

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30 July 2017

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30 July 2017

volume

14

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30 July 2017

issue

2

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30 July 2017

page(s)

R65

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Dating the emergence of pandemic influenza viruses

30 July 2017

cites work

1 reference

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5 July 2018

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Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant

5 July 2018

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5 July 2018

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5 July 2018

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Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans

5 July 2018

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5 July 2018

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Protective role of activated protein C in lung and airway remodeling.

5 July 2018

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5 July 2018

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Engineering the proteolytic specificity of activated protein C improves its pharmacological properties

5 July 2018

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5 July 2018

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Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line

5 July 2018

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5 July 2018

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Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

5 July 2018

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5 July 2018

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Distinct functions of activated protein C differentially attenuate acute kidney injury.

5 July 2018

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29 October 2018

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Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1.

29 October 2018

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Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia

29 October 2018

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29 October 2018

Protein C in pneumonia

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Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin.

29 October 2018

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29 October 2018

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Disturbed alveolar fibrin turnover during pneumonia is restricted to the site of infection.

29 October 2018

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Severe protein C deficiency predicts early death in severe sepsis

29 October 2018

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Effects of drotrecogin alfa (activated) in human endotoxemia

29 October 2018

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Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia

29 October 2018

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29 October 2018

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Pharmacokinetic-pharmacodynamic analysis of drotrecogin alfa (activated) in patients with severe sepsis

29 October 2018

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Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia

29 October 2018

1 reference

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A simple, sensitive spectrophotometric assay for extrinsic (tissue-type) plasminogen activator applicable to measurements in plasma

29 October 2018

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12 December 2020

Evidence for the occurrence of a fast-acting inhibitor for tissue-type plasminogen activator in human plasma

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12 December 2020

Whole blood clot lysis: in vitro modulation by activated protein C

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12 December 2020

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12 December 2020

Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats

1 reference

12 December 2020

The profibrinolytic effect of activated protein C in clots formed from plasma is TAFI-dependent

1 reference

12 December 2020

Activated protein C prevents LPS-induced pulmonary vascular injury by inhibiting cytokine production

1 reference

12 December 2020

Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis

1 reference

12 December 2020

Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats

1 reference

12 December 2020

Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation

1 reference

12 December 2020

Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats*

1 reference

12 December 2020

Biomarkers of thrombosis, fibrinolysis, and inflammation in patients with severe sepsis due to community-acquired pneumonia with and without Streptococcus pneumoniae

1 reference

12 December 2020

Alveolar Fibrin Formation Caused by Enhanced Procoagulant and Depressed Fibrinolytic Capacities in Severe Pneumonia

1 reference

12 December 2020

Enhanced tissue factor pathway activity and fibrin turnover in the alveolar compartment of patients with interstitial lung disease

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC8964

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30 July 2017

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30 July 2017

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