Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome (Q33916170)

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2 February 2020

title

Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome (English)

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2 February 2020

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2

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2 February 2020

Hans-Joachim Anders

series ordinal

4

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2 February 2020

author name string

Murthy Narayana Darisipudi

series ordinal

1

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2 February 2020

Khader Valli Rupanagudi

series ordinal

3

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2 February 2020

language of work or name

English

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publication date

23 May 2011

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2 February 2020

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2 February 2020

volume

6

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issue

5

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2 February 2020

page(s)

e19588

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Creative Commons Attribution 4.0 International

2 February 2020

copyright license

start time

23 May 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

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Cryopyrin activates the inflammasome in response to toxins and ATP

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Gout-associated uric acid crystals activate the NALP3 inflammasome

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Identification of novel pharmacological activities of an antifungal agent, nystatin, to promote dendritic cell maturation.

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Nystatin induces secretion of interleukin (IL)-1beta, IL-8, and tumor necrosis factor alpha by a toll-like receptor-dependent mechanism

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Modification of prostanoid secretion in endothelial cells by amphotericin B acting synergistically with interleukin-1beta: possible explanation of proinflammatory effects.

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

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The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

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Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

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(1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages

21 January 2018

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Altered cytokine production in mice lacking P2X(7) receptors

21 January 2018

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Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal -Glucan

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10.1371/JOURNAL.PONE.0019588

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21625424 AND SRC:MED&resulttype=core&format=json

2 February 2020

0 references

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2 February 2020

PubMed publication ID

21625424

1 reference