Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation. (Q33913278)

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3 February 2020

title

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation (English)

1 reference

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3 February 2020

0 references

1 reference

Curled Dmel_CG31299

1 reference

CCR4-NOT transcription complex subunit 3 Dmel_CG8426

1 reference

CCR4-NOT transcription complex subunit 10 Dmel_CG18616

1 reference

author

Lianbing Zhang

2

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3 February 2020

Elmar Wahle

8

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3 February 2020

author name string

Claudia Temme

1

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3 February 2020

Elisabeth Kremmer

3

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3 February 2020

Christian Ihling

4

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3 February 2020

Aymeric Chartier

5

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3 February 2020

Andrea Sinz

6

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3 February 2020

Martine Simonelig

7

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language of work or name

English

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publication date

26 May 2010

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3 February 2020

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3 February 2020

volume

16

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issue

7

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3 February 2020

page(s)

1356-1370

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Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation

3 February 2020

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1 reference

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BTG/TOB factors impact deadenylases

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The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release

5 July 2018

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Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

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The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation

5 July 2018

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Curled encodes the Drosophila homolog of the vertebrate circadian deadenylase Nocturnin

5 July 2018

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Human Ccr4-Not complexes contain variable deadenylase subunits

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The Ccr4-Pop2-NOT mRNA deadenylase contributes to septin organization in Saccharomyces cerevisiae

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Bicaudal-C associates with a Trailer Hitch/Me31B complex and is required for efficient Gurken secretion

5 July 2018

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5 July 2018

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5 July 2018

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Nascent peptide-dependent translation arrest leads to Not4p-mediated protein degradation by the proteasome

5 July 2018

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The Drosophila melanogaster Gene cg4930 Encodes a High Affinity Inhibitor for Endonuclease G.

5 July 2018

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5 July 2018

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Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

5 July 2018

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Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins

5 July 2018

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S. cerevisiae Vts1p induces deadenylation-dependent transcript degradation and interacts with the Ccr4p-Pop2p-Not deadenylase complex

5 July 2018

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A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

5 July 2018

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mRNA silencing in human erythroid cell maturation: heterogeneous nuclear ribonucleoprotein K controls the expression of its regulator c-Src

5 July 2018

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PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila

5 July 2018

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The BTG2 protein is a general activator of mRNA deadenylation

5 July 2018

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Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth

5 July 2018

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5 July 2018

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5 July 2018

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CCR4/NOT complex associates with the proteasome and regulates histone methylation

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes

5 July 2018

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Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos

5 July 2018

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Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4.

5 July 2018

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The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex

5 July 2018

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Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.

5 July 2018

1 reference

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mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

5 July 2018

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5 July 2018

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PUF proteins bind Pop2p to regulate messenger RNAs

5 July 2018

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Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

5 July 2018

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General translational repression by activators of mRNA decapping

5 July 2018

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Conservation of the deadenylase activity of proteins of the Caf1 family in human

5 July 2018

1 reference

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Messenger RNA turnover in eukaryotes: pathways and enzymes

5 July 2018

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A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila

5 July 2018

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The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?

5 July 2018

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Mapping the topology and determination of a low-resolution three-dimensional structure of the calmodulin-melittin complex by chemical cross-linking and high-resolution FTICRMS: direct demonstration of multiple binding modes

5 July 2018

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The enzymes and control of eukaryotic mRNA turnover

5 July 2018

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Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression

5 July 2018

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X-ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex

5 July 2018

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Global control of gene expression in yeast by the Ccr4-Not complex

5 July 2018

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The CCR4-NOT complex plays diverse roles in mRNA metabolism

5 July 2018

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The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators

5 July 2018

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Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA.

5 July 2018

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Identification of multiple RNA features that influence CCR4 deadenylation activity

5 July 2018

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Nocturnin, a deadenylase in Xenopus laevis retina: a mechanism for posttranscriptional control of circadian-related mRNA.

5 July 2018

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Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

5 July 2018

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CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase

5 July 2018

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Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex

5 July 2018

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Functional organization of the yeast proteome by systematic analysis of protein complexes

5 July 2018

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A conserved role of a DEAD box helicase in mRNA masking

5 July 2018

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Identification of four families of yCCR4- and Mg2 -dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding

5 July 2018

1 reference

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Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex

5 July 2018

1 reference

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The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

5 July 2018

1 reference

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Drosophila Brain Tumor is a translational repressor

5 July 2018

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The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

5 July 2018

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Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits

5 July 2018

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The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

5 July 2018

1 reference

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The Drosophila poly(A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro

5 July 2018

1 reference

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Dhh1p, a Putative RNA Helicase, Associates with the General Transcription Factors Pop2p and Ccr4p from Saccharomyces cerevisiae

5 July 2018

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Preferential deadenylation of Hsp70 mRNA plays a key role in regulating Hsp70 expression in Drosophila melanogaster

5 July 2018

1 reference

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Cell-free deadenylation assays with Drosophila embryo extracts

5 July 2018

1 reference

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Drosophila processing bodies in oogenesis

29 October 2018

1 reference

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A deadenylation negative feedback mechanism governs meiotic metaphase arrest.

29 October 2018

1 reference

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Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes.

29 October 2018

1 reference

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Degradation of hsp70 and other mRNAs in Drosophila via the 5' 3' pathway and its regulation by heat shock

29 October 2018

1 reference

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Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germline

29 October 2018

1 reference

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The Drosophila PNG kinase complex regulates the translation of cyclin B.

29 October 2018

1 reference

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PUF protein-mediated deadenylation is catalyzed by Ccr4p.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

Rapid ATP-dependent deadenylation of nanos mRNA in a cell-free system from Drosophila embryos

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

Efficient protein trafficking requires trailer hitch, a component of a ribonucleoprotein complex localized to the ER in Drosophila

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

An essential cytoplasmic function for the nuclear poly(A) binding protein, PABP2, in poly(A) tail length control and early development in Drosophila

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

twin, a CCR4 homolog, regulates cyclin poly(A) tail length to permit Drosophila oogenesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

Systematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

bicaudal encodes the Drosophila beta NAC homolog, a component of the ribosomal translational machinery*.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885685

Interaction between Not1p, a component of the Ccr4-not complex, a global regulator of transcription, and Dhh1p, a putative RNA helicase

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20504953

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multifunctional deadenylase complexes diversify mRNA control

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20504953

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The essential function of Not1 lies within the Ccr4-Not complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20504953

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1261/RNA.2145110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20504953 AND SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20504953 AND SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

20504953

1 reference