Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding. (Q33896745)

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5 November 2019

title

Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding (English)

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5 November 2019

6

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5 November 2019

author name string

Das B

1

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5 November 2019

Shu X

2

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5 November 2019

Day GJ

3

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5 November 2019

Han J

4

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5 November 2019

Krishna UM

5

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5 November 2019

Broek D

7

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5 November 2019

language of work or name

English

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publication date

1 May 2000

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Journal of Biological Chemistry

5 November 2019

published in

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5 November 2019

volume

275

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issue

20

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5 November 2019

page(s)

15074-15081

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Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

5 November 2019

cites work

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Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

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Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

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Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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Lck regulates Vav activation of members of the Rho family of GTPases

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Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains

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A cell's sense of direction

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Signalling through phosphoinositide 3-kinases: the lipids take centre stage

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The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.

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Lymphocyte signalling: a coordinating role for Vav?

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Vav links antigen-receptor signaling to the actin cytoskeleton

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Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

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Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function

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Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases.

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A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

21 January 2018

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Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

21 January 2018

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Structure and mutagenesis of the Dbl homology domain

21 January 2018

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The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains

21 January 2018

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Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

21 January 2018

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Identification of the ras GTPase-activating protein GAP1(m) as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo

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Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

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Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase

21 January 2018

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Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

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The PH domain and the polybasic c domain of cytohesin-1 cooperate specifically in plasma membrane association and cellular function

21 January 2018

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Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.

21 January 2018

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

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Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

21 January 2018

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Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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Involvement of the pleckstrin homology domain in the insulin-stimulated activation of protein kinase B.

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Phospholipid-binding protein domains

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M907269199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10748082 AND SRC:MED&resulttype=core&format=json

5 November 2019

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