Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium (Q33890748)

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English	Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

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author name string

Meili R

1

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Europe PubMed Central

PubMed publication ID

29 July 2017

Ellsworth C

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

Lee S

3

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Europe PubMed Central

PubMed publication ID

29 July 2017

Reddy TB

4

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Europe PubMed Central

PubMed publication ID

29 July 2017

Ma H

5

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Europe PubMed Central

PubMed publication ID

29 July 2017

Firtel RA

6

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Europe PubMed Central

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29 July 2017

language of work or name

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publication date

1 April 1999

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Europe PubMed Central

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29 July 2017

The EMBO Journal

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Europe PubMed Central

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29 July 2017

18

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Europe PubMed Central

PubMed publication ID

29 July 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2092-2105

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Localization of two phosphorylation sites adjacent to a region important for polymerization on the tail of Dictyostelium myosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

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5 July 2018

Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

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5 July 2018

Role of translocation in the activation and function of protein kinase B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium

1 reference

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5 July 2018

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

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5 July 2018

Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation

1 reference

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5 July 2018

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

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5 July 2018

The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

cGMP as second messenger during Dictyostelium chemotaxis

1 reference

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5 July 2018

Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42

1 reference

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5 July 2018

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Identification of detergent-resistant plasma membrane microdomains in dictyostelium: enrichment of signal transduction proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Interacting signaling pathways controlling multicellular development in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Signaling through chemoattractant receptors in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Molecular genetics of signal transduction in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Chemoattractant-mediated increases in cGMP induce changes in Dictyostelium myosin II heavy chain-specific protein kinase C activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Transduction of the chemotactic cAMP signal across the plasma membrane of Dictyostelium cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

The Dictyostelium cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

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5 July 2018

The surface cyclic AMP receptors, cAR1, cAR2, and cAR3, promote Ca2 influx in Dictyostelium discoideum by a G alpha 2-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

A transformation vector for dictyostelium discoideum with a new selectable marker bsr.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

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5 July 2018

CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Two cAMP receptors activate common signaling pathways in Dictyostelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase

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5 July 2018

The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Integration of signaling information in controlling cell-fate decisions in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

The regulation of Dictyostelium development by transmembrane signalling.

1 reference

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5 July 2018

Excitation, adaption, and deadaptation of the cAMP-mediated cGMP Response in dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

5 July 2018

Disruption of Dictyostelium PI3K genes reduces [32P]phosphatidylinositol 3,4 bisphosphate and [32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

Signal transduction and motility of Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

Membrane binding of myristylated peptides corresponding to the NH2 terminus of Src.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

Serpentine cAMP receptors may act through a G protein-independent pathway to induce postaggregative development in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171294

29 October 2018

Phosphorylation of Chemoattractant Receptors Is Not Essential for Chemotaxis or Termination of G-protein-mediated Responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein signaling events are activated at the leading edge of chemotactic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dictyostelium myosin II is regulated during chemotaxis by a novel protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane signaling in Dictyostelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seven helix cAMP receptors stimulate Ca2 entry in the absence of functional G proteins in Dictyostelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of guanylyl cyclase by a cGMP-binding protein during chemotaxis in Dictyostelium discoideum

1 reference

https://pubmed.ncbi.nlm.nih.gov/10205164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/18.8.2092

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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