Dividing the empire: boundary chromatin elements delimit the territory of enhancers (Q33890226)

29 July 2017

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title

Dividing the empire: boundary chromatin elements delimit the territory of enhancers (English)

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29 July 2017

Udvardy A

1

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29 July 2017

language of work or name

English

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publication date

1 January 1999

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29 July 2017

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29 July 2017

volume

18

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29 July 2017

issue

1

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29 July 2017

page(s)

1-8

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Chromatin interaction mechanism of transcriptional control in vivo

29 July 2017

cites work

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5 July 2018

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The scs and scs' insulator elements impart a cis requirement on enhancer-promoter interactions

5 July 2018

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5 July 2018

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5 July 2018

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A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1.

5 July 2018

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5 July 2018

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5 July 2018

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Sheltering of gamma-globin expression from position effects requires both an upstream locus control region and a regulatory element 3' to the A gamma-globin gene

5 July 2018

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The activity of the scs and scs' insulator elements is not dependent on chromosomal context

5 July 2018

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A locus control region at -12 kb of the tyrosinase gene

5 July 2018

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5 July 2018

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Interaction between mutations in the suppressor of Hairy wing and modifier of mdg4 genes of Drosophila melanogaster affecting the phenotype of gypsy-induced mutations

5 July 2018

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5 July 2018

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Genetic and molecular analysis of the gypsy chromatin insulator of Drosophila

5 July 2018

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Tissue-specific factors additively increase the probability of the all-or-none formation of a hypersensitive site.

5 July 2018

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Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.

5 July 2018

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Effects of the su(Hw) insulator protein on the expression of the divergently transcribed Drosophila yolk protein genes

5 July 2018

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The human growth hormone gene is regulated by a multicomponent locus control region

5 July 2018

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Far upstream regions of class II MHC Ea are necessary for position-independent, copy-dependent expression of Ea transgene

5 July 2018

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The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects.

5 July 2018

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Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice

5 July 2018

1 reference

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A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

5 July 2018

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The dynamics of chromatin condensation: redistribution of topoisomerase II in the 87A7 heat shock locus during induction and recovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Developmental regulation of human beta-globin gene transcription: a switch of loyalties?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

The 5' flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

SARs stimulate but do not confer position independent gene expression

5 July 2018

1 reference

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Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice.

5 July 2018

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Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice

5 July 2018

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Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions.

5 July 2018

1 reference

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Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domain

5 July 2018

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Visualization of chromosomal domains with boundary element-associated factor BEAF-32.

5 July 2018

1 reference

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Position-dependent variegation of globin transgene expression in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

The suppressor of Hairy-wing protein regulates the tissue-specific expression of the Drosophila gypsy retrotransposon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

A drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Enhancers increase the probability but not the level of gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Targeting gene expression to haemopoietic stem cells: a chromatin-dependent upstream element mediates cell type-specific expression of the stem cell antigen CD34.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Participation of the human beta-globin locus control region in initiation of DNA replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

The "beta-like-globin" gene domain in human erythroid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

A developmentally stable chromatin structure in the human beta-globin gene cluster

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

The Drosophila melanogaster suppressor of Hairy-wing protein binds to specific sequences of the gypsy retrotransposon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Mutant gene phenotypes mediated by a Drosophila melanogaster retrotransposon require sequences homologous to mammalian enhancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Novel genes influencing the expression of the yellow locus and mdg4 (gypsy) in Drosophila melanogaster.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Suppression in Drosophila: su(Hw) and su(f) gene products interact with a region of gypsy (mdg4) regulating its transcriptional activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

The chicken lysozyme 5' matrix attachment region increases transcription from a heterologous promoter in heterologous cells and dampens position effects on the expression of transfected genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Globin gene regulation and switching: circa 1990.

5 July 2018

1 reference

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Potentiation of a polyadenylylation site by a downstream protein-DNA interaction

5 July 2018

1 reference

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Hypersensitive site 4 of the human beta globin locus control region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes

5 July 2018

1 reference

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A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation

5 July 2018

1 reference

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Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster

5 July 2018

1 reference

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A position-effect assay for boundaries of higher order chromosomal domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Dynamic chromatin: The regulatory domain organization of eukaryotic gene loci

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

The nucleoskeleton and the topology of replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

A group of scs elements function as domain boundaries in an enhancer-blocking assay

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

DNA position-specific repression of transcription by a Drosophila zinc finger protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Polycomb and Trithorax Group Proteins Mediate the Function of a Chromatin Insulator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

A leucine zipper domain of the suppressor of Hairy-wing protein mediates its repressive effect on enhancer function

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171096

A locus control region in the T cell receptor alpha/delta locus

29 October 2018

1 reference

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Transcription complex stability and chromatin dynamics in vivo

29 October 2018

1 reference

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Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

29 October 2018

1 reference

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Hypersensitive site 5 of the human beta locus control region functions as a chromatin insulator

29 October 2018

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12 December 2020

Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

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12 December 2020

A nuclear DNA attachment element mediates elevated and position-independent gene activity

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12 December 2020

Transcriptional enhancers act in cis to suppress position-effect variegation

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12 December 2020

Locus control region function and heterochromatin-induced position effect variegation

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/18.1.1

1 reference

29 July 2017

1 reference

29 July 2017

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