Activation of the unfolded protein response bypasses trastuzumab-mediated inhibition of the PI-3K pathway (Q33880386)

29 July 2017

title

Activation of the unfolded protein response bypasses trastuzumab-mediated inhibition of the PI-3K pathway (English)

1 reference

29 July 2017

Sreekanth Kumandan

1

1 reference

29 July 2017

Navin R Mahadevan

2

1 reference

29 July 2017

Kevin Chiu

3

1 reference

29 July 2017

Alexandra DeLaney

4

1 reference

29 July 2017

Maurizio Zanetti

5

1 reference

29 July 2017

language of work or name

English

0 references

publication date

28 November 2012

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29 July 2017

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29 July 2017

volume

329

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29 July 2017

issue

2

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29 July 2017

page(s)

236-242

1 reference

The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells

29 July 2017

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28 July 2018

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Lipocalin 2 in cancer: When good immunity goes bad

28 July 2018

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Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

28 July 2018

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Trastuzumab has preferential activity against breast cancers driven by HER2 homodimers

28 July 2018

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Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis

28 July 2018

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Resistance to Trastuzumab in Breast Cancer.

28 July 2018

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Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis

28 July 2018

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Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response

28 July 2018

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TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection.

28 July 2018

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Lipocalin 2 promotes breast cancer progression

28 July 2018

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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

28 July 2018

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The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis

28 July 2018

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Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer.

28 July 2018

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28 July 2018

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Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study

28 July 2018

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Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer

28 July 2018

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

28 July 2018

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Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

28 July 2018

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Transcriptional and translational control in the Mammalian unfolded protein response

28 July 2018

1 reference

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Mechanism of action of trastuzumab and scientific update

28 July 2018

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28 July 2018

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

28 July 2018

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SV40-induced expression of mouse gene 24p3 involves a post-transcriptional mechanism

28 July 2018

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Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product

28 July 2018

1 reference

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ER stress drives Lipocalin 2 upregulation in prostate cancer cells in an NF-κB-dependent manner

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091625

Unfolded protein response activation contributes to chemoresistance in hepatocellular carcinoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091625

Activation and clinical significance of the unfolded protein response in breast cancer

29 October 2018

1 reference

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Tissue microarray-based study of patients with lymph node-negative breast cancer shows that HER2/neu overexpression is an important predictive marker of poor prognosis

29 October 2018

1 reference

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Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium

29 October 2018

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Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

29 October 2018

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29 October 2018

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The association between Akt activation and resistance to hormone therapy in metastatic breast cancer

29 October 2018

1 reference

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Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091625

Inhibition of the sarcoplasmic reticulum Ca2 transport ATPase by thapsigargin at subnanomolar concentrations

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23200669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Breast cancer--loss of PTEN predicts resistance to treatment

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23200669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CANLET.2012.11.014

1 reference

29 July 2017

1 reference

29 July 2017

1 reference