Why AMD is a disease of ageing and not of development: mechanisms and insights (Q33879659)

29 July 2017

title

Why AMD is a disease of ageing and not of development: mechanisms and insights (English)

1 reference

29 July 2017

Kaushal Sharma

1

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29 July 2017

Neel Kamal Sharma

series ordinal

2

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29 July 2017

Akshay Anand

series ordinal

3

1 reference

29 July 2017

publication date

10 July 2014

1 reference

Frontiers in Aging Neuroscience

29 July 2017

published in

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29 July 2017

volume

6

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29 July 2017

page(s)

151

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Does DcR1 (TNF-related apoptosis-inducing-ligand Receptor 3) have any role in human AMD pathogenesis?

29 July 2017

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5 July 2018

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Association of Variants in theLIPCandABCA1Genes with Intermediate and Large Drusen and Advanced Age-Related Macular Degeneration

5 July 2018

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Role of the immediate early response 3 (IER3) gene in cellular stress response, inflammation and tumorigenesis

5 July 2018

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Serum Lipid Biomarkers and Hepatic Lipase Gene Associations with Age-Related Macular Degeneration

5 July 2018

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5 July 2018

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5 July 2018

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Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration

5 July 2018

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7-ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NFκB but independently of reactive oxygen species formation

5 July 2018

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Abundant lipid and protein components of drusen

5 July 2018

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Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

5 July 2018

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Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol

5 July 2018

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The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited

5 July 2018

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7-ketocholesterol induces endoplasmic reticulum stress in HT-29 cells

5 July 2018

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Decline in genomic DNA methylation through aging in a cohort of elderly subjects

5 July 2018

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7-Ketocholesterol is present in lipid deposits in the primate retina: potential implication in the induction of VEGF and CNV formation

5 July 2018

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5 July 2018

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5 July 2018

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7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent

5 July 2018

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Inherited complement regulatory protein deficiency predisposes to human disease in acute injury and chronic inflammatory statesthe examples of vascular damage in atypical hemolytic uremic syndrome and debris accumulation in age-related macular degen

5 July 2018

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5 July 2018

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Drusen complement components C3a and C5a promote choroidal neovascularization

5 July 2018

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5 July 2018

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Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration

5 July 2018

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5 July 2018

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5 July 2018

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Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy

5 July 2018

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Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

5 July 2018

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Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation

5 July 2018

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Accumulation of cholesterol with age in human Bruch's membrane.

5 July 2018

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5 July 2018

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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

5 July 2018

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Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

5 July 2018

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Genetic association of apolipoprotein E with age-related macular degeneration

5 July 2018

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The epsilon4 allele of the apolipoprotein E gene as a potential protective factor for exudative age-related macular degeneration

5 July 2018

1 reference

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5 July 2018

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5 July 2018

1 reference

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5 July 2018

1 reference

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Clinico-morphologic correlations of drusen of Bruch's membrane

5 July 2018

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5 July 2018

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5 July 2018

1 reference

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Correlation between biochemical composition and fluorescein binding of deposits in Bruch's membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091411

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

5 July 2018

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Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

5 July 2018

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Cholesterol-dependent human complement activation resulting in damage to liposomal model membranes.

5 July 2018

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The epsilon2 and epsilon4 alleles of the apolipoprotein gene are associated with age-related macular degeneration

5 July 2018

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Accelerated evolution of brain atrophy and "black holes" in MS patients with APOE-epsilon 4.

21 January 2018

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Arteriosclerosis, apolipoprotein E, and Alzheimer's disease.

21 January 2018

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Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.

21 January 2018

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Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols

21 January 2018

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Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization

21 January 2018

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Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemica

21 January 2018

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Single nucleotide polymorphism and serum levels of VEGFR2 are associated with age related macular degeneration.

21 January 2018

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CC chemokine receptor-3 as new target for age-related macular degeneration

21 January 2018

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Correlation between serum lipids and age-related macular degeneration: a case-control study

21 January 2018

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Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.

29 October 2018

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Effects of cholesterol and apolipoprotein E on retinal abnormalities in ApoE-deficient mice

29 October 2018

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Time course of oxysterol formation during in vitro oxidation of low density lipoprotein

29 October 2018

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Singlet oxygen intermediacy in the photodynamic action of membrane-bound hematoporphyrin derivative

10 December 2018

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12 December 2020

Prognostic significance of the immediate early response gene X-1 (IEX-1) expression in pancreatic cancer

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12 December 2020

A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy

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12 December 2020

Generation of complement anaphylatoxins and C5b-9 by crystalline cholesterol oxidation derivatives depends on hydroxyl group number and position

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12 December 2020

Activation of the alternative pathway of complement by microcrystalline cholesterol

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12 December 2020

Expression of vascular endothelial growth factor and its receptors in inflamed and vascularized human corneas

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12 December 2020

Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study

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12 December 2020

Vascular endothelial growth factor plasma levels before and after treatment of neovascular age-related macular degeneration with bevacizumab or ranibizumab

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12 December 2020

Changes in lipid metabolism in women with age-related macular degeneration

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12 December 2020

Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages

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12 December 2020

Ultrastructural changes in Bruch's membrane of apolipoprotein E-deficient mice

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12 December 2020

25-Hydroxycholesterol, 7β-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages

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12 December 2020

WITHDRAWN: Complement dysregulation in AMD: RPE-Bruch's membrane-choroid

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.MAM.2012.03.011

Identifiers

DOI

10.3389/FNAGI.2014.00151

1 reference

29 July 2017

1 reference

29 July 2017

1 reference