The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain (Q33876994)

29 July 2017

title

The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain (English)

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29 July 2017

S D Shumway

1

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29 July 2017

M Maki

series ordinal

2

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29 July 2017

S Miyamoto

series ordinal

3

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29 July 2017

language of work or name

English

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publication date

1 October 1999

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Journal of Biological Chemistry

29 July 2017

published in

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29 July 2017

volume

274

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29 July 2017

issue

43

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29 July 2017

page(s)

30874-30881

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Peptide sequences that target cytosolic proteins for lysosomal proteolysis

29 July 2017

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The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

21 January 2018

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Structure of an IkappaBalpha/NF-kappaB complex

21 January 2018

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

21 January 2018

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

21 January 2018

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

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Calpain contributes to silica-induced IkB-a degradation and nuclear factor-kB activation

21 January 2018

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Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

21 January 2018

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Novel IκBα Proteolytic Pathway in WEHI231 Immature B Cells

21 January 2018

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Calpain: a protease in search of a function?

21 January 2018

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21 January 2018

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Calpains: Intact and active?

21 January 2018

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Regulation of the calpain-calpastatin system by membranes (review).

21 January 2018

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Calmodulin-binding proteins as calpain substrates.

21 January 2018

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Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

21 January 2018

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Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required

21 January 2018

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Requirement of different subdomains of calpastatin for calpain inhibition and for binding to calmodulin-like domains

21 January 2018

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Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines

21 January 2018

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Studies on the Structure and Function of the Avian Sarcoma Virus Transforming-gene Product

21 January 2018

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Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

21 January 2018

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity

21 January 2018

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Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

21 January 2018

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N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

Distinct domains of IkappaBalpha regulate c-Rel in the cytoplasm and in the nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

Constitutive phosphorylation of I kappa B alpha by casein kinase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

p34Cdc28-mediated control of Cln3 cyclin degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

A PEST-Like Sequence Mediates Phosphorylation and Efficient Ubiquitination of Yeast Uracil Permease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

The signal response of IkappaB alpha is regulated by transferable N- and C-terminal domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

PEST sequences and regulation by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

PEST sequences do not influence substrate susceptibility to calpain proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

PEST motifs are not required for rapid calpain-mediated proteolysis of c-fos protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

Deletion of the PEST-like region of photosystem two modifies the QB-binding pocket but does not prevent rapid turnover of D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IκBα/NF-κB pathway in limb-girdle muscular dystrophy type 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

A non-disruptive technique for loading calcium buffers and indicators into cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.274.43.30874

21 January 2018

Identifiers

DOI

10.1074/JBC.274.43.30874

1 reference

29 July 2017

1 reference