Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing (Q33875102)

29 July 2017

title

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing (English)

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29 July 2017

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8

Martin J Aryee

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29 July 2017

9

J Keith Joung

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29 July 2017

Shengdar Q Tsai

1

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29 July 2017

Nicolas Wyvekens

2

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29 July 2017

Cyd Khayter

3

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29 July 2017

Jennifer A Foden

4

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29 July 2017

Vishal Thapar

5

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29 July 2017

Deepak Reyon

6

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29 July 2017

Mathew J Goodwin

7

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29 July 2017

publication date

25 April 2014

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29 July 2017

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volume

32

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29 July 2017

issue

6

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29 July 2017

page(s)

569-576

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CRISPR-Cas systems for editing, regulating and targeting genomes

29 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

CRISPR RNA-guided activation of endogenous human genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

DNA targeting specificity of RNA-guided Cas9 nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

APOBEC3B is an enzymatic source of mutation in breast cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Efficient genome editing in zebrafish using a CRISPR-Cas system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

RNA-guided human genome engineering via Cas9

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

TALENs: a widely applicable technology for targeted genome editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

FLASH assembly of TALENs for high-throughput genome editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Mechanism of substrate selection by a highly specific CRISPR endoribonuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Genome editing with engineered zinc finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Fast and accurate short read alignment with Burrows-Wheeler transform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

An improved zinc-finger nuclease architecture for highly specific genome editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090141

Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/NBT.2908

21 January 2018

Identifiers

DOI

10.1038/NBT.2908

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29 July 2017

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29 July 2017

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