Minimalist and universal peptidomimetics. (Q33869896)

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28 January 2020

review article

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title

Minimalist and universal peptidomimetics (English)

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3

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author name string

Eunhwa Ko

series ordinal

1

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28 January 2020

Jing Liu

series ordinal

2

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publication date

11 April 2011

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28 January 2020

published in

Chemical Society Reviews

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volume

40

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issue

8

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page(s)

4411-4421

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A hot spot of binding energy in a hormone-receptor interface

28 January 2020

cites work

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Peptidomimetics and peptide backbone modifications

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Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes

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1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors

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A highly stable short alpha-helix constrained by a main-chain hydrogen-bond surrogate

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Concepts and progress in the development of peptide mimetics

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Effect of progressive benzyl substitution on the conformations of aminocaproic acid-cyclized dipeptides.

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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Molecular properties that influence the oral bioavailability of drug candidates

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Identification of potential small molecule peptidomimetics similar to motifs in proteins.

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Protein-protein interfaces: architectures and interactions in protein-protein interfaces and in protein cores. Their similarities and differences

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Anatomy of hot spots in protein interfaces

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The atomic structure of protein-protein recognition sites

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Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues

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Hot spots--a review of the protein-protein interface determinant amino-acid residues

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Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.

21 January 2018

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Design and application of an alpha-helix-mimetic scaffold based on an oligoamide-foldamer strategy: antagonism of the Bak BH3/Bcl-xL complex

21 January 2018

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Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry

21 January 2018

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Recognition of solvent exposed protein surfaces using anthracene derived receptors

21 January 2018

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Synthetic non-peptide mimetics of alpha-helices

21 January 2018

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Benzoylurea oligomers: synthetic foldamers that mimic extended alpha helices

21 January 2018

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Targeting protein-protein interactions by rational design: mimicry of protein surfaces

21 January 2018

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Biphenyls as potential mimetics of protein alpha-helix

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21 January 2018

Aromatic delta-peptides

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Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells

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Synthesis of pyridazine-based scaffolds as alpha-helix mimetics

21 January 2018

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Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions

21 January 2018

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Toward proteomimetics: terphenyl derivatives as structural and functional mimics of extended regions of an alpha-helix

21 January 2018

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Terphenyl-based helical mimetics that disrupt the p53/HDM2 interaction

21 January 2018

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Application of a Theory of Enzyme Specificity to Protein Synthesis

21 January 2018

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On the attribution and additivity of binding energies

21 January 2018

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Universal peptidomimetics.

21 January 2018

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A combinatorial method for solution-phase synthesis of labeled bivalent beta-turn mimics.

21 January 2018

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Design, synthesis, and evaluation of Phe-Gly mimetics: heterocyclic building blocks for pseudopeptides

21 January 2018

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New oxazole-based peptidomimetics: useful building blocks for the synthesis of orthogonally protected macrocyclic scaffolds

21 January 2018

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Synthesis of a small library of diketopiperazines as potential inhibitors of calpain.

21 January 2018

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Bivalent peptidomimetic ligands of TrkC are biased agonists and selectively induce neuritogenesis or potentiate neurotrophin-3 trophic signals

21 January 2018

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Pyrrole-Based Scaffolds for Turn Mimics

21 January 2018

1 reference

Dynamical search for bis-penicillamine enkephalin conformations

21 January 2018

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Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 2. Macrocyclic hexapyrrolinones

21 January 2018

1 reference

Diastereoselective Synthesis of ψ[(E)-CHCMe]- and ψ[(Z)-CHCMe]-Type Dipeptide Isosteres by Organocopper-Mediatedanti-SN2‘ Reaction

21 January 2018

1 reference

A Cyclic Metallopeptide Induces α Helicity in Short Peptide Fragments of Thermolysin

21 January 2018

1 reference

Consecutive Cyclic Pentapeptide Modules Form Shortα-Helices that are Very Stable to Water and Denaturants

21 January 2018

1 reference

Peptide and Protein Recognition by Designed Molecules

21 January 2018

1 reference

Summing Up Ligand Binding Interactions

21 January 2018

1 reference

A potent cyclic hexapeptide analogue of somatostatin

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1039/C0CS00218F

1 reference

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28 January 2020

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