Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse (Q33862948)

29 July 2017

title

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse (English)

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29 July 2017

7

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29 July 2017

Greenberg RA

1

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29 July 2017

Chin L

2

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29 July 2017

Femino A

3

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29 July 2017

Lee KH

4

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29 July 2017

Gottlieb GJ

5

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29 July 2017

Singer RH

6

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29 July 2017

DePinho RA

8

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29 July 2017

language of work or name

English

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publication date

1 May 1999

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29 July 2017

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29 July 2017

volume

97

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29 July 2017

issue

4

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29 July 2017

page(s)

515-525

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p14ARF links the tumour suppressors RB and p53.

29 July 2017

cites work

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7 January 2021

Telomerase and cell proliferation in mouse skin papillomas.

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Localization of ASH1 mRNA particles in living yeast

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7 January 2021

Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis

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7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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Extension of life-span by introduction of telomerase into normal human cells

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Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation

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7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

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7 January 2021

The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit

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7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

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7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

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7 January 2021

Evolution of cell senescence, atherosclerosis and benign tumours

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7 January 2021

Visualization of single RNA transcripts in situ

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7 January 2021

Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

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7 January 2021

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

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7 January 2021

Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1.

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

The serial cultivation of human diploid cell strains

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

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7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

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7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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7 January 2021

Mouse minor satellite DNA genetically maps to the centromere and is physically linked to the proximal telomere

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

Spontaneous immortalization rate of cultured Chinese hamster cells.

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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7 January 2021

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

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7 January 2021

An alternative pathway for yeast telomere maintenance rescues est1- senescence

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7 January 2021

Expression of mouse telomerase catalytic subunit in embryos and adult tissues.

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7 January 2021

Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase

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7 January 2021

Circular chromosome formation in a fission yeast mutant defective in two ATM homologues

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7 January 2021

Two modes of survival of fission yeast without telomerase.

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7 January 2021

Severe growth defect in mouse cells lacking the telomerase RNA component

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7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

Developmental and tissue-specific regulation of mouse telomerase and telomere length

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation

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7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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7 January 2021

Senescence as a mode of tumor suppression

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7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

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7 January 2021

A role for both RB and p53 in the regulation of human cellular senescence

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7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

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7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

Myc activates telomerase

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7 January 2021

Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?

1 reference

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7 January 2021

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(00)80761-8

7 January 2021

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/S0092-8674(00)80761-8

Identifiers

DOI

10.1016/S0092-8674(00)80761-8

1 reference

release_4yxpsxwmt5dspfltes5iio5lka

29 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/4yxpsxwmt5dspfltes5iio5lka

24 November 2022

mapped directly with Wikidata item

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