Structure and function of phosphatidylinositol-3,4 kinase (Q33855352)

29 July 2017

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title

Structure and function of phosphatidylinositol-3,4 kinase (English)

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29 July 2017

Funaki M

1

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29 July 2017

Katagiri H

2

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29 July 2017

Inukai K

3

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29 July 2017

Kikuchi M

4

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29 July 2017

Asano T

5

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29 July 2017

publication date

1 March 2000

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29 July 2017

number of pages

8

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inferred from page(s)

published in

Cellular Signalling

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29 July 2017

volume

12

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29 July 2017

issue

3

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29 July 2017

page(s)

135-142

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Receptor tyrosine kinases and their targets

29 July 2017

cites work

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7 January 2021

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

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7 January 2021

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

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7 January 2021

The effects of wortmannin, a potent inhibitor of phosphatidylinositol 3-kinase, on insulin-stimulated glucose transport, GLUT4 translocation, antilipolysis, and DNA synthesis

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7 January 2021

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

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7 January 2021

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

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7 January 2021

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

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7 January 2021

Involvement of phosphatidylinositol-3 kinase in prevention of low K( )-induced apoptosis of cerebellar granule neurons

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7 January 2021

Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase

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7 January 2021

Targeting of constitutively active phosphoinositide 3-kinase to GLUT4-containing vesicles in 3T3-L1 adipocytes

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7 January 2021

Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells

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7 January 2021

Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes

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7 January 2021

Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes

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7 January 2021

SH2 domains recognize specific phosphopeptide sequences

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7 January 2021

Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system

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7 January 2021

The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase

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7 January 2021

A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK Is generated by alternative splicing of the p85alpha gene

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7 January 2021

Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain

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7 January 2021

p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin

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7 January 2021

Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene

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7 January 2021

Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle

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7 January 2021

Isolation and characterization of the droPIK57 gene encoding a new regulatory subunit of phosphatidylinositol 3-kinase from Drosophila melanogaster

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Crystal structure of a Src-homology 3 (SH3) domain

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Solution structure of the SH3 domain of phospholipase C-gamma

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Solution structure of the SH3 domain of Src and identification of its ligand-binding site

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

The GTPase dynamin binds to and is activated by a subset of SH3 domains

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminals

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Structural organization of the bcr gene and its role in the Ph' translocation

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Bcr encodes a GTPase-activating protein for p21rac

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Intermolecular interactions of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase.

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7 January 2021

Phosphoinositide 3-Kinase Binds Constitutively to / -Tubulin and Binds to -Tubulin in Response to Insulin

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7 January 2021

Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton

1 reference

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7 January 2021

Beta-tubulin binds Src homology 2 domains through a region different from the tyrosine-phosphorylated protein-recognizing site

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7 January 2021

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

The v-Src SH3 Domain Binds Phosphatidylinositol 3'-Kinase

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7 January 2021

Identification of amino acid residues required for a specific interaction between Src-tyrosine kinase and proline-rich region of phosphatidylinositol-3' kinase

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Growth factor signaling by receptor tyrosine kinases

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Role of IRS-2 in insulin and cytokine signalling

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

p110δ, a novel phosphoinositide 3-kinase in leukocytes

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Structure and function of phosphatidylinositol 3-kinase: a potential second messenger system involved in growth control

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Structural analysis of a novel isoform of phosphoinositide 3OH-kinase

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7 January 2021

Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain

1 reference

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7 January 2021

Cloning, expression, and localization of 230-kDa phosphatidylinositol 4-kinase

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7 January 2021

The phosphatidylinositol 4-phosphate 5-kinase family.

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7 January 2021

Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

Phosphoinositide 3-kinase: A new effector in signal transduction?

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7 January 2021

FYVE fingers bind PtdIns(3)P

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7 January 2021

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

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7 January 2021

Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger

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7 January 2021

Hrs-2 is an ATPase implicated in calcium-regulated secretion

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7 January 2021

Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast

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7 January 2021

VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae

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7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

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7 January 2021

Activation of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate

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7 January 2021

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

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7 January 2021

Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains

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7 January 2021

Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase

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7 January 2021

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

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7 January 2021

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

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7 January 2021

Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate

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7 January 2021

The mammalian profilin isoforms display complementary affinities for PIP2 and proline-rich sequences

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7 January 2021

A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway

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7 January 2021

Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand

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7 January 2021

Phosphoinositide binding domains: embracing 3-phosphate

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7 January 2021

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

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7 January 2021

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

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7 January 2021

Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function

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7 January 2021

Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

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7 January 2021

Regulation of CapZ, an actin capping protein of chicken muscle, by anionic phospholipids

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7 January 2021

Regulation of Profilin Localization in Saccharomyces cerevisiae by Phosphoinositide Metabolism

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7 January 2021

Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion.

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7 January 2021

Phosphatidylinositol 4-kinase, but not phosphatidylinositol 3-kinase, is present in GLUT4-containing vesicles isolated from rat skeletal muscle

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7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

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https://api.crossref.org/works/10.1016/S0898-6568(99)50086-8

7 January 2021

10.1016/S0898-6568(99)00086-8

Identifiers

DOI

1 reference

29 July 2017

1 reference