Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins (Q33855277)

29 July 2017

title

Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins (English)

1 reference

29 July 2017

Akiko Takeda

1

1 reference

29 July 2017

Nayan J Sarma

series ordinal

2

1 reference

29 July 2017

Anmaar M Abdul-Nabi

series ordinal

3

1 reference

29 July 2017

Nabeel R Yaseen

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

16 March 2010

1 reference

Journal of Biological Chemistry

29 July 2017

published in

1 reference

29 July 2017

volume

285

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29 July 2017

issue

21

1 reference

29 July 2017

page(s)

16248-16257

1 reference

Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9

29 July 2017

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Nup214 is required for CRM1-dependent nuclear protein export in vivo

5 July 2018

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NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34 hematopoietic cells

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The role of NUP98 gene fusions in hematologic malignancy

5 July 2018

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5 July 2018

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Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358.

5 July 2018

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Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export

5 July 2018

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The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells

5 July 2018

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Nup98 is a mobile nucleoporin with transcription-dependent dynamics

5 July 2018

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The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR.

5 July 2018

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NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

5 July 2018

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The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import

5 July 2018

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Dynamics of NF kappa B and Ikappa Balpha studied with green fluorescent protein (GFP) fusion proteins. Investigation of GFP-p65 binding to DNa by fluorescence resonance energy transfer.

5 July 2018

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The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1

5 July 2018

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5 July 2018

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Two distinct classes of Ran-binding sites on the nucleoporin Nup-358

5 July 2018

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RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains

5 July 2018

1 reference

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CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

5 July 2018

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Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev

5 July 2018

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Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export

5 July 2018

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Nucleocytoplasmic Shuttling Factors Including Ran and CRM1 Mediate Nuclear Export of NFAT In Vitro

5 July 2018

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The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10

5 July 2018

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The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

5 July 2018

1 reference

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Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871492

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

Purification of RanGDP, RanGTP, and RanGMPPNP by ion exchange chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

Carrier-independent nuclear import of the transcription factor PU.1 via RanGTP-stimulated binding to Nup153.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

CRM1-mediated nuclear export: to the pore and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

Aberrant intracellular localization of SET-CAN fusion protein, associated with a leukemia, disorganizes nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M109.048785

Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871492

Leukemogenic properties of NUP98-PMX1 are linked to NUP98 and homeodomain sequence functions but not to binding properties of PMX1 to serum response factor

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20233715

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20233715

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20233715

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.048785

1 reference

29 July 2017

1 reference

29 July 2017

1 reference