Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT. (Q33853052)

29 July 2017

title

Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT. (English)

1 reference

29 July 2017

1 reference

Tiffany G Bredfeldt

1

1 reference

29 July 2017

K Leigh Greathouse

2

1 reference

29 July 2017

Stephen H Safe

3

1 reference

29 July 2017

Mien-Chie Hung

4

1 reference

29 July 2017

Mark T Bedford

5

1 reference

29 July 2017

Cheryl L Walker

6

1 reference

29 July 2017

publication date

29 March 2010

1 reference

29 July 2017

published in

Molecular Endocrinology

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29 July 2017

volume

24

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29 July 2017

issue

5

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29 July 2017

page(s)

993-1006

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Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms

29 July 2017

cites work

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axis

28 July 2018

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28 July 2018

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Developmental exposure to diethylstilbestrol alters uterine gene expression that may be associated with uterine neoplasia later in life

28 July 2018

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28 July 2018

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Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

28 July 2018

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28 July 2018

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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

28 July 2018

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Activation of kinase pathways in MCF-7 cells by 17beta-estradiol and structurally diverse estrogenic compounds

28 July 2018

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Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting

28 July 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

28 July 2018

1 reference

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The diverse functions of histone lysine methylation

28 July 2018

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Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3

28 July 2018

1 reference

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Signaling regulation of genomic and nongenomic functions of estrogen receptors.

28 July 2018

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Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance

28 July 2018

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Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes

28 July 2018

1 reference

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Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer

28 July 2018

1 reference

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Role of protein methylation in regulation of transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Estrogen receptor-alpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly

28 July 2018

1 reference

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The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.

28 July 2018

1 reference

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

28 July 2018

1 reference

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An epigenetic road map for histone lysine methylation

28 July 2018

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Oestrogen receptor knockout mice: roles for oestrogen receptors alpha and beta in reproductive tissues

28 July 2018

1 reference

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The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

28 July 2018

1 reference

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Transdominant suppression of estrogen receptor signaling by progesterone receptor ligands in uterine leiomyoma cells

28 July 2018

1 reference

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Histone methylation: dynamic or static?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase

28 July 2018

1 reference

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Production and actions of estrogens

28 July 2018

1 reference

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Identification of novel oestrogen receptor target genes in human ZR75-1 breast cancer cells by expression profiling

28 July 2018

1 reference

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A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

28 July 2018

1 reference

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Mechanisms of estrogen action

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Cell localization, physiology, and nongenomic actions of estrogen receptors

28 July 2018

1 reference

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Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

28 July 2018

1 reference

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The multifaceted mechanisms of estradiol and estrogen receptor signaling.

28 July 2018

1 reference

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Gene imprinting in developmental toxicology: a possible interface between physiology and pathology

28 July 2018

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Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

28 July 2018

1 reference

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28 July 2018

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1 reference

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Differential effects of estradiol and estradiol-BSA conjugates

28 July 2018

1 reference

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Developmental effects of estrogenic chemicals are predicted by an in vitro assay incorporating modification of cell uptake by serum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

28 July 2018

1 reference

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Developmental effects of endocrine-disrupting chemicals in wildlife and humans

28 July 2018

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Insights from the study of animals lacking functional estrogen receptor

28 July 2018

1 reference

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Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo

28 July 2018

1 reference

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Sex hormones and neoplasia: genotoxic effects in short term assays.

28 July 2018

1 reference

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Diethylstilbestrol and Estradiol Binding to Serum Albumin and Pregnancy Plasma of Rat and Human*

28 July 2018

1 reference

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PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

28 July 2018

1 reference

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Identification of uterine leiomyoma genes developmentally reprogrammed by neonatal exposure to diethylstilbestrol

29 October 2018

1 reference

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A model for transmission of the H3K27me3 epigenetic mark

29 October 2018

1 reference

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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

29 October 2018

1 reference

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A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation

29 October 2018

1 reference

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Estrogen response element-independent estrogen receptor (ER)-alpha signaling does not rescue sexual behavior but restores normal testosterone secretion in male ERalpha knockout mice.

29 October 2018

1 reference

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Identification of a sensitive period for developmental programming that increases risk for uterine leiomyoma in Eker rats

29 October 2018

1 reference

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Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Functional cooperation between HP1 and DNMT1 mediates gene silencing.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

17beta-estradiol protects cortical neurons against oxidative stress-induced cell death through reduction in the activity of mitogen-activated protein kinase and in the accumulation of intracellular calcium

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

The epigenetic magic of histone lysine methylation

29 October 2018

1 reference

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Estrogen receptors and human disease

29 October 2018

1 reference

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Estrogen receptors and cell signaling

29 October 2018

1 reference

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Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation.

29 October 2018

1 reference

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Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins

29 October 2018

1 reference

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Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens

29 October 2018

1 reference

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Developmental exposure to diethylstilbestrol (DES) alters uterine response to estrogens in prepubescent mice: low versus high dose effects

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Neonatal diethylstilbestrol exposure induces persistent elevation of c-fos expression and hypomethylation in its exon-4 in mouse uterus

29 October 2018

1 reference

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Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity

29 October 2018

1 reference

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Reversal of bone loss in mice by nongenotropic signaling of sex steroids

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Characterization of uterine leiomyomas in CD-1 mice following developmental exposure to diethylstilbestrol (DES).

29 October 2018

1 reference

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Development of cDNA microarray for expression profiling of estrogen-responsive genes

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Cellular functions of plasma membrane estrogen receptors

29 October 2018

1 reference

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Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation

29 October 2018

1 reference

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

29 October 2018

1 reference

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Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870935

Rapid activation of endothelial nitric oxide synthase by estrogen

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20351197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen/antiestrogen responsiveness in an in vivo/in vitro model for myometrial tumorigenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20351197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

17Beta-estradiol induced Ca2 influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20351197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/ME.2009-0438

1 reference

29 July 2017

1 reference

29 July 2017

1 reference