Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts (Q33847524)

29 July 2017

title

Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts (English)

1 reference

29 July 2017

main subject

protein ubiquitination

1 reference

Jan Kottwitz

3

0 references

Christine Klein

7

object named as

Christine Klein

1 reference

29 July 2017

6

Katja Lohmann

1 reference

29 July 2017

Aleksandar Rakovic

1

1 reference

29 July 2017

Anne Grünewald

2

1 reference

29 July 2017

Norbert Brüggemann

4

1 reference

29 July 2017

Peter P Pramstaller

5

1 reference

29 July 2017

language of work or name

English

0 references

publication date

8 March 2011

1 reference

29 July 2017

1 reference

29 July 2017

volume

6

1 reference

29 July 2017

issue

3

1 reference

29 July 2017

page(s)

e16746

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

8 March 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3050809/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

5 July 2018

1 reference

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PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

5 July 2018

1 reference

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

5 July 2018

1 reference

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Analysis of differential DNA damage in the mitochondrial genome employing a semi-long run real-time PCR approach

5 July 2018

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Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

5 July 2018

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Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

5 July 2018

1 reference

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Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.

5 July 2018

1 reference

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Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio).

5 July 2018

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Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells

5 July 2018

1 reference

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Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Mitophagy in yeast occurs through a selective mechanism

5 July 2018

1 reference

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The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

5 July 2018

1 reference

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Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view

5 July 2018

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Ubiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion

5 July 2018

1 reference

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The PINK1/Parkin pathway regulates mitochondrial morphology

5 July 2018

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Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder

5 July 2018

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Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050809

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

5 July 2018

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Global approaches to understanding ubiquitination

5 July 2018

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Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers

5 July 2018

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Structural basis of mitochondrial tethering by mitofusin complexes.

5 July 2018

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Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress

5 July 2018

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Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

5 July 2018

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5 July 2018

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A cryptic protease couples deubiquitination and degradation by the proteasome

5 July 2018

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5 July 2018

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The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

5 July 2018

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0016746

Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis.

21 January 2018

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0016746

Bilateral subthalamic stimulation in Parkin and PINK1 parkinsonism.

21 January 2018

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Assaying degradation and deubiquitination of a ubiquitinated substrate by purified 26S proteasomes

21 January 2018

1 reference

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Isolation and characterization of tightly coupled mitochondria from neurons and astrocytes in primary culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0016746

Mitochondrial complex I deficiency in Parkinson's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21408142

12 December 2020

inferred from PubMed ID database lookup

Clinical Spectrum of Homozygous and Heterozygous PINK1 Mutations in a Large German Family With Parkinson Disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21408142

12 December 2020

inferred from PubMed ID database lookup

Coexistence of mutations in PINK1 and mitochondrial DNA in early onset parkinsonism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21408142

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0016746

1 reference

29 July 2017

0 references

1 reference

29 July 2017

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