Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis (Q33837133)

29 July 2017

title

Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

29 July 2017

main subject

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1 reference

Marcelo R Vargas

1

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29 July 2017

Delinda A Johnson

2

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29 July 2017

Daniel W Sirkis

3

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29 July 2017

Albee Messing

4

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29 July 2017

Jeffrey A Johnson

5

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29 July 2017

language of work or name

English

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publication date

1 December 2008

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29 July 2017

published in

Journal of Neuroscience

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29 July 2017

volume

28

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29 July 2017

issue

50

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29 July 2017

page(s)

13574-13581

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2866507/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.

4 July 2018

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Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury

4 July 2018

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Role of Nrf2 in protection against intracerebral hemorrhage injury in mice

4 July 2018

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis

4 July 2018

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29 October 2018

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Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis

29 October 2018

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Co-culture of neurones with glutathione deficient astrocytes leads to increased neuronal susceptibility to nitric oxide and increased glutamate-cysteine ligase activity

29 October 2018

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Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

29 October 2018

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

29 October 2018

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Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site

29 October 2018

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Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons

29 October 2018

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Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism

29 October 2018

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GFAP promoter directs astrocyte-specific expression in transgenic mice

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866507

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

29 October 2018

1 reference

12 December 2020

A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

1 reference

12 December 2020

Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis

1 reference

12 December 2020

GFAP promoter elements required for region-specific and astrocyte-specific expression

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione

1 reference

12 December 2020

10.1523/JNEUROSCI.4099-08.2008

Identifiers

DOI

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29 July 2017

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29 July 2017

1 reference