Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling (Q33836897)

29 July 2017

title

Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling (English)

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29 July 2017

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reactive oxygen species

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5

Roger J Davis

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29 July 2017

Brooke M Emerling

1

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29 July 2017

Leonidas C Platanias

2

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29 July 2017

Emma Black

3

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29 July 2017

Angel R Nebreda

4

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29 July 2017

Navdeep S Chandel

6

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29 July 2017

language of work or name

English

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publication date

1 June 2005

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Molecular and Cellular Biology

29 July 2017

published in

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29 July 2017

volume

25

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29 July 2017

issue

12

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29 July 2017

page(s)

4853-4862

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Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules

29 July 2017

cites work

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4 July 2018

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4 July 2018

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Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species

4 July 2018

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p38 signaling-mediated hypoxia-inducible factor 1 alpha and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells

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4 July 2018

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4 July 2018

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Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

4 July 2018

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4 July 2018

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

4 July 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

4 July 2018

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Rac1 activity is required for the activation of hypoxia-inducible factor 1.

4 July 2018

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Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses

4 July 2018

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Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis

4 July 2018

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4 July 2018

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4 July 2018

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

4 July 2018

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Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

4 July 2018

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Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells

4 July 2018

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4 July 2018

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4 July 2018

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

4 July 2018

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

4 July 2018

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Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing

4 July 2018

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

4 July 2018

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

4 July 2018

1 reference

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JunD reduces tumor angiogenesis by protecting cells from oxidative stress

4 July 2018

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Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite

29 October 2018

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Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes

29 October 2018

1 reference

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The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine

29 October 2018

1 reference

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Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases

29 October 2018

1 reference

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GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140591

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140591

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

29 October 2018

1 reference

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Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15923604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15923604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15923604

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.25.12.4853-4862.2005

1 reference

29 July 2017

1 reference

29 July 2017

1 reference