The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure. (Q33836365)

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11 January 2020

title

The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure (English)

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11 January 2020

2

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4

Kai W Wucherpfennig

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11 January 2020

author name string

David Garrity

series ordinal

1

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11 January 2020

Jianwen Feng

series ordinal

3

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11 January 2020

language of work or name

English

0 references

publication date

13 May 2005

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Proceedings of the National Academy of Sciences of the United States of America

11 January 2020

published in

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volume

102

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issue

21

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11 January 2020

page(s)

7641-7646

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Convergence on a distinctive assembly mechanism by unrelated families of activating immune receptors.

11 January 2020

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4 July 2018

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Roles of the NKG2D immunoreceptor and its ligands

4 July 2018

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Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis

4 July 2018

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Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein

4 July 2018

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Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity

4 July 2018

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NKG2D ligands: unconventional MHC class I‐like molecules exploited by viruses and cancer

4 July 2018

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Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein

4 July 2018

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Symmetry recognizing asymmetry: analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and MHC class I-like ligands

4 July 2018

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The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3

4 July 2018

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The organizing principle in the formation of the T cell receptor-CD3 complex.

4 July 2018

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Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D

4 July 2018

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NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation

4 July 2018

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Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.

4 July 2018

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The role of the NKG2D immunoreceptor in immune cell activation and natural killing

4 July 2018

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Lymphocyte activation via NKG2D: towards a new paradigm in immune recognition?

4 July 2018

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Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors

4 July 2018

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Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D

4 July 2018

1 reference

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Regulation of cutaneous malignancy by gammadelta T cells

4 July 2018

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Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo

4 July 2018

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Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

4 July 2018

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Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA

4 July 2018

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ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

4 July 2018

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Polar residues drive association of polyleucine transmembrane helices

4 July 2018

1 reference

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Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells

4 July 2018

1 reference

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Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A

4 July 2018

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Polar side chains drive the association of model transmembrane peptides

4 July 2018

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Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice

4 July 2018

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An activating immunoreceptor complex formed by NKG2D and DAP10

4 July 2018

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Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

4 July 2018

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Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB

4 July 2018

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Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity

4 July 2018

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Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors

4 July 2018

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In Vitro Translation and Assembly of a Complete T Cell Receptor–CD3 Complex

4 July 2018

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A second lineage of mammalian major histocompatibility complex class I genes

4 July 2018

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Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

4 July 2018

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Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

4 July 2018

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A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease.

4 July 2018

1 reference

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Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0502439102

NKG2D blockade prevents autoimmune diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0502439102

Direct observation of ligand recognition by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0502439102

MCMV glycoprotein gp40 confers virus resistance to CD8 T cells and NK cells in vivo.

21 January 2018

1 reference

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Cutting Edge: Down-Regulation of MICA on Human Tumors by Proteolytic Shedding

21 January 2018

1 reference

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Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

21 January 2018

1 reference

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Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15894612

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0502439102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15894612 AND SRC:MED&resulttype=core&format=json

11 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15894612 AND SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

15894612

1 reference