Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice. (Q33817373)

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English	Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice.	scientific article

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23 March 2020

Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice (English)

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23 March 2020

steatohepatitis

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Helene L Kammoun

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23 March 2020

Michael J Kraakman

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23 March 2020

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23 March 2020

Stefan Rose-John

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23 March 2020

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Tamara Louise Allen

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23 March 2020

Darren Colin Henstridge

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23 March 2020

Mark Anthony Febbraio

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23 March 2020

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20 June 2017

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23 March 2020

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23 March 2020

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23 March 2020

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23 March 2020

e0179099

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23 March 2020

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Creative Commons Attribution 4.0 International

20 June 2017

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April 2022 Public Data File from Crossref

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Adipose tissue-liver axis in alcoholic liver disease

1 reference

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Nonalcoholic fatty liver disease: a systematic review

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4 July 2018

Activation of the GP130-STAT3 axis and its potential implications in nonalcoholic fatty liver disease

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Adipose tissue inflammation in glucose metabolism

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4 July 2018

Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production

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4 July 2018

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4 July 2018

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4 July 2018

IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis

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4 July 2018

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

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4 July 2018

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

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4 July 2018

Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma

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4 July 2018

Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478123

4 July 2018

Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses

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Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease

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21 January 2018

Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis

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21 January 2018

Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

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Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice

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Interleukin-6-deficient mice develop mature-onset obesity

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Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1.

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Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice.

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PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue

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Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients

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1 reference

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1 reference

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10.1371/JOURNAL.PONE.0179099

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Europe PubMed Central

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23 March 2020

2017PLoSO..1279099K

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23 March 2020

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23 March 2020

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