Interpretation of the biological relevance of genotoxicity test results: the importance of thresholds (Q33816103)

29 July 2017

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title

Interpretation of the biological relevance of genotoxicity test results: the importance of thresholds (English)

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29 July 2017

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Kirkland DJ

1

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29 July 2017

Müller L

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 January 2000

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29 July 2017

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29 July 2017

volume

464

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29 July 2017

issue

1

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29 July 2017

page(s)

137-147

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The quality of genotoxicity testing of drugs. Experiences of a regulatory agency with new and old compounds

29 July 2017

cites work

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Towards a validation of the micronucleus test

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Chromosomal aberrations in V79 hamster cells induced by hyperosmotic solutions of NaCl

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Low pH leads to sister-chromatid exchanges and chromosomal aberrations, and its clastogenicity is S-dependent

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Sodium azide mutagenesis in mammals: inability of mammalian cells to convert azide to a mutagenic intermediate

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Series: current issues in mutagenesis and carcinogenesis, No. 65. The genotoxicity and carcinogenicity of paracetamol: a regulatory (re)view

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Recommendations for spacing of test chemical concentrations in the mouse lymphoma tk mutation assay (MLA)

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Discrimination between genotoxicity and cytotoxicity in the induction of DNA double-strand breaks in cells treated with etoposide, melphalan, cisplatin, potassium cyanide, Triton X-100, and gamma-irradiation

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DNA synthesis inhibition as an indirect mechanism of chromosome aberrations: comparison of DNA-reactive and non-DNA-reactive clastogens

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Effects of high osmotic strength on chromosome aberrations, sister-chromatid exchanges and DNA strand breaks, and the relation to toxicity

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Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: analysis by pulsed field gel electrophoresis and implications for alkaline elution assays.

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Identifiers

DOI

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29 July 2017

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