DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer (Q33815545)

24948741

29 July 2017

title

DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer (English)

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29 July 2017

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George Sledge

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Tomasz Mandat

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Renata Duchnowska

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Stephan Woditschka

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Ewa Szutowicz-Zielińska

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Ewa Szutowicz-Zielińska

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Yongzhen Qian

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Lynda Evans

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L Tiffany Reed

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Diane Palmieri

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Sunil Badve

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Brunilde Gril

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Mirit I Aladjem

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Haiqing Fu

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Natasha M Flores

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Waldemar Och

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Bogumiła Czartoryska-Arlukowicz

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James B Mitchell

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language of work or name

English

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publication date

19 June 2014

1 reference

24948741

Journal of the National Cancer Institute

29 July 2017

published in

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volume

106

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9 June 2020

issue

7

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A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

9 June 2020

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The combination of chemotherapy with HVJ-E containing Rad51 siRNA elicited diverse anti-tumor effects and synergistically suppressed melanoma

4 July 2018

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4 July 2018

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

4 July 2018

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4 July 2018

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BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

4 July 2018

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Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

4 July 2018

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Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

4 July 2018

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Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome

4 July 2018

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

4 July 2018

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Real-time imaging reveals the single steps of brain metastasis formation

4 July 2018

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Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks

4 July 2018

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Latent bone metastasis in breast cancer tied to Src-dependent survival signals

4 July 2018

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The vascular basement membrane as "soil" in brain metastasis

4 July 2018

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Genes that mediate breast cancer metastasis to the brain

4 July 2018

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PALB2 is an integral component of the BRCA complex required for homologous recombination repair

4 July 2018

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PALB2 links BRCA1 and BRCA2 in the DNA-damage response

4 July 2018

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Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer: high incidence of central nervous system metastases

4 July 2018

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Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization

4 July 2018

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4 July 2018

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4 July 2018

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HSV-1 amplicon-mediated post-transcriptional inhibition of Rad51 sensitizes human glioma cells to ionizing radiation

4 July 2018

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Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain

4 July 2018

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Mechanism of homologous recombination: mediators and helicases take on regulatory functions

4 July 2018

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Is there more to BARD1 than BRCA1?

4 July 2018

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4 July 2018

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4 July 2018

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Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

4 July 2018

1 reference

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BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks

4 July 2018

1 reference

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Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

4 July 2018

1 reference

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Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

4 July 2018

1 reference

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BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export

4 July 2018

1 reference

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Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis

4 July 2018

1 reference

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Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073622

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

4 July 2018

1 reference

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In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene

4 July 2018

1 reference

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Astrocyte-derived cytokines contribute to the metastatic brain specificity of breast cancer cells

4 July 2018

1 reference

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Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

4 July 2018

1 reference

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Identification of a RING protein that can interact in vivo with the BRCA1 gene product

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073622

Instability and decay of the primary structure of DNA

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073622

Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER.

4 July 2018

1 reference

Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma

21 January 2018

1 reference

In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain

21 January 2018

1 reference

Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells.

21 January 2018

1 reference

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

21 January 2018

1 reference

BRCA1 DNA-binding activity is stimulated by BARD1.

21 January 2018

1 reference

Cancer. Complicated supercomplexes

21 January 2018

1 reference

Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/JNCI/DJU145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24948741 AND SRC:MED&resulttype=core&format=json

9 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24948741 AND SRC:MED&resulttype=core&format=json

9 June 2020

24948741

1 reference

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