Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia. (Q33815424)

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20 December 2019

title

Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia (English)

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20 December 2019

3

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20 December 2019

author name string

Rafal Pawlinski

1

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20 December 2019

Brian Pedersen

2

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20 December 2019

Michael Tencati

4

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20 December 2019

Todd Holscher

5

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20 December 2019

William Boisvert

6

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20 December 2019

Patricia Andrade-Gordon

7

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20 December 2019

Rolf Dario Frank

8

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20 December 2019

Nigel Mackman

9

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20 December 2019

language of work or name

English

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publication date

23 October 2003

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20 December 2019

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20 December 2019

volume

103

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20 December 2019

issue

4

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20 December 2019

page(s)

1342-1347

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Novel strategies for the treatment of sepsis

20 December 2019

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Essential role for proteinase-activated receptor-2 in arthritis

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4 July 2018

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Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor

4 July 2018

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Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha

4 July 2018

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Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor 1.

4 July 2018

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4 July 2018

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Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing inflammation

4 July 2018

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Delayed onset of inflammation in protease-activated receptor-2-deficient mice

4 July 2018

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Therapeutic rationale for antithrombin III in sepsis

4 July 2018

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Tissue factor inhibition and clinical trial results of tissue factor pathway inhibitor in sepsis

4 July 2018

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Thrombin signalling and protease-activated receptors

4 July 2018

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Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

4 July 2018

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Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo

4 July 2018

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Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis

4 July 2018

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Lipopolysaccharide induction of tissue factor expression in rabbits

4 July 2018

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Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1

4 July 2018

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Exacerbation of antigen-induced arthritis in urokinase-deficient mice

4 July 2018

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A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state

4 July 2018

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The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex

4 July 2018

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Low levels of tissue factor are compatible with development and hemostasis in mice.

4 July 2018

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Biological consequences of thrombin receptor deficiency in mice.

4 July 2018

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The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor

4 July 2018

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Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock

4 July 2018

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4 July 2018

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Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice.

30 October 2018

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Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation

30 October 2018

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Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells

30 October 2018

1 reference

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Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: a multicenter, randomized, placebo-controlled, single-blind, dose escalation study.

30 October 2018

1 reference

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Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and PAR4 agonists

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860856

Generation of a humanized, high affinity anti-tissue factor antibody for use as a novel antithrombotic therapeutic.

30 October 2018

1 reference

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Endotoxin-induced disseminated intravascular coagulation in rabbits: Effect of recombinant hirudin on hemostatic parameters, fibrin deposits, and mortality

30 October 2018

1 reference

12 December 2020

Active site inhibited factor VIIa (DEGR VIIa) attenuates the coagulant and interleukin-6 and -8, but not tumor necrosis factor, responses of the baboon to LD100 Escherichia coli

1 reference

12 December 2020

Disseminated intravascular coagulation

1 reference

12 December 2020

Hirudin reduces tissue factor expression in neointima after balloon injury in rabbit femoral and porcine coronary arteries

1 reference

12 December 2020

Pretreatment of Rabbits With Either Hirudin, Ancrod, or Warfarin Significantly Reduces the Immediate Uptake of Fibrinogen and Platelets by the Deendothelialized Aorta Wall After Balloon-Catheter Injury In Vivo

1 reference

12 December 2020

Impact of antithrombin deficiency in thrombogenesis: lipopolysaccharide and stress-induced thrombus formation in heterozygous antithrombin-deficient mice

1 reference

12 December 2020

10.1182/BLOOD-2003-09-3051

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576054 AND SRC:MED&resulttype=core&format=json

20 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14576054 AND SRC:MED&resulttype=core&format=json

20 December 2019

PubMed publication ID

14576054

1 reference