Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase (Q33807866)

29 July 2017

title

Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase (English)

1 reference

29 July 2017

P L Boyer

1

1 reference

29 July 2017

S H Hughes

series ordinal

2

1 reference

29 July 2017

language of work or name

1 reference

1 July 2000

1 reference

29 July 2017

number of pages

7

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Virology

1 reference

29 July 2017

volume

74

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29 July 2017

issue

14

1 reference

29 July 2017

page(s)

6494-6500

1 reference

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase

29 July 2017

cites work

1 reference

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Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

28 July 2018

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

28 July 2018

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Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

28 July 2018

1 reference

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Increased misincorporation fidelity observed for nucleoside analog resistance mutations M184V and E89G in human immunodeficiency virus type 1 reverse transcriptase does not correlate with the overall error rate measured in vitro

28 July 2018

1 reference

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The impact of multidideoxynucleoside resistance-conferring mutations in human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and error specificity

28 July 2018

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HIV genetic variation is directed and restricted by DNA precursor availability.

28 July 2018

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Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89

28 July 2018

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Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

28 July 2018

1 reference

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Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis

28 July 2018

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Analyzing fidelity of DNA polymerases.

28 July 2018

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Mutagenesis by transient misalignment.

28 July 2018

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Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase

28 July 2018

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The accuracy of reverse transcriptase from HIV-1.

28 July 2018

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Misalignment-mediated DNA synthesis errors

28 July 2018

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Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates

28 July 2018

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Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural RNA

28 July 2018

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Fidelity of HIV-1 reverse transcriptase copying RNA in vitro

28 July 2018

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Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase.

28 July 2018

1 reference

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Analyzing the fidelity of reverse transcription and transcription.

30 October 2018

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Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection

30 October 2018

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Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots

30 October 2018

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Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain.

30 October 2018

1 reference

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Mechanism of HIV-1 reverse transcriptase. Termination of processive synthesis on a natural DNA template is influenced by the sequence of the template-primer stem

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10864662

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10864662

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.74.14.6494-6500.2000

1 reference

29 July 2017

1 reference

29 July 2017

1 reference