Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium. (Q33791667)

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English	Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium.	scientific article

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4 March 2020

Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium (English)

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4 March 2020

phase I clinical trial

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4 March 2020

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John M Maris

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4 March 2020

Judith G Villablanca

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Judith G Villablanca

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4 March 2020

Katherine K Matthay

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Katherine K Matthay

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Susan Groshen

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4 March 2020

Scarlett Czarnecki

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Scarlett Czarnecki

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Araz Marachelian

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Araz Marachelian

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4 March 2020

Fariba Goodarzian

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Fariba Goodarzian

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4 March 2020

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Barry J Maurer

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4 March 2020

Jitka Janeba

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4 March 2020

Paul M Sondel

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4 March 2020

Hollie A Jackson

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4 March 2020

Hiroyuki Shimada

11

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4 March 2020

Beth Hasenauer

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publication date

29 June 2013

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4 March 2020

Pediatric Blood & Cancer

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4 March 2020

60

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4 March 2020

11

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4 March 2020

1801-1808

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4 March 2020

Phase II study of oral capsular 4-hydroxyphenylretinamide (4-HPR/fenretinide) in pediatric patients with refractory or recurrent neuroblastoma: a report from the Children's Oncology Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Identification of dihydroceramide desaturase as a direct in vitro target for fenretinide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Comparison of ¹²³I-metaiodobenzylguanidine (MIBG) and ¹³¹I-MIBG semi-quantitative scores in predicting survival in patients with stage 4 neuroblastoma: a report from the Children's Oncology Group

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Phase II study of irinotecan and temozolomide in children with relapsed or refractory neuroblastoma: a Children's Oncology Group study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Iodine-131--metaiodobenzylguanidine double infusion with autologous stem-cell rescue for neuroblastoma: a new approaches to neuroblastoma therapy phase I study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Improved oral delivery of N-(4-hydroxyphenyl)retinamide with a novel LYM-X-SORB organized lipid complex

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Fenretinide cytotoxicity for Ewing's sarcoma and primitive neuroectodermal tumor cell lines is decreased by hypoxia and synergistically enhanced by ceramide modulators

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Inhibition of neuroblastoma-induced angiogenesis by fenretinide

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Involvement of Reactive Oxygen Species in N-(4-Hydroxyphenyl)retinamide-Induced Apoptosis in Cervical Carcinoma Cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Phase I/II trial of tamoxifen with or without fenretinide, an analog of vitamin A, in women with metastatic breast cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Five-year administration of fenretinide: pharmacokinetics and effects on plasma retinol concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Prospects of chemoprevention of human cancers with the synthetic retinoid fenretinide

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

4 July 2018

Role of antioxidants and intracellular free radicals in retinamide-induced cell death.

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https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Phase I trial of oral fenretinide in children with high-risk solid tumors: a report from the Children's Oncology Group (CCG 09709).

1 reference

https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Phase II trial of fenretinide (NSC 374551) in patients with recurrent small cell lung cancer

1 reference

https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Statistical properties of the traditional algorithm-based designs for phase I cancer clinical trials

1 reference

https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Liquid chromatography method for quantifying N-(4-hydroxyphenyl)retinamide and N-(4-methoxyphenyl)retinamide in tissues

1 reference

https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Langerhans cell histiocytosis in a patient with stage 4 neuroblastoma receiving oral fenretinide.

1 reference

https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Metastatic sites in stage IV and IVS neuroblastoma correlate with age, tumor biology, and survival

1 reference

https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Correlation of early metastatic response by 123I-metaiodobenzylguanidine scintigraphy with overall response and event-free survival in stage IV neuroblastoma.

1 reference

https://api.crossref.org/works/10.1002/PBC.24643

21 January 2018

Phase I trial and pharmacokinetics of fenretinide in children with neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066886

30 October 2018

Safety of the synthetic retinoid fenretinide: long-term results from a controlled clinical trial for the prevention of contralateral breast cancer

1 reference

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30 October 2018

Higher potency of N-(4-hydroxyphenyl)retinamide than all-trans-retinoic acid in induction of apoptosis in non-small cell lung cancer cell lines

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30 October 2018

Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment.

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30 October 2018

Phase I trial of fenretinide lym-x-sorb oral powder in adults with solid tumors and lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerability of the synthetic retinoid Fenretinide (HPR)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of N-(4-hydroxyphenyl)-retinamide on the number and cytotoxicity of natural killer cells in vitamin-A-sufficient and -deficient rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic retinoid fenretinide is effective against a human ovarian carcinoma xenograft and potentiates cisplatin activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fenretinide (4-HPR) in chemoprevention of oral leukoplakia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new 123I-MIBG whole body scan scoring method--application to the prediction of the response of metastases to induction chemotherapy in stage IV neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I evaluation of all-trans retinoic acid with and without ketoconazole in adults with solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23813912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PBC.24643

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Europe PubMed Central

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4 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23813912 AND SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23813912 AND SRC:MED&resulttype=core&format=json

4 March 2020

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