Genome-wide association study of PR interval (Q33772170)

29 July 2017

title

Genome-wide association study of PR interval (English)

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genome-wide association study

29 July 2017

main subject

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author

Fernando Rivadeneira

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Bertram Müller-Myhsok

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Cornelia M. van Duijn

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Cornelia M van Duijn

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David Schlessinger

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David Schlessinger

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André Uitterlinden

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André G Uitterlinden

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Serena Sanna

60

Serena Sanna

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Eric Boerwinkle

50

Eric Boerwinkle

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Manuela Uda

46

Manuela Uda

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Emelia J. Benjamin

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Emelia J Benjamin

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Anna Köttgen

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Anna Köttgen

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Christopher Newton-Cheh

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Christopher Newton-Cheh

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40

Gudny Eiriksdottir

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Jan A Kors

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Jan A Kors

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Kathryn L Lunetta

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Albert V. Smith

Albert Vernon Smith

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Alvaro Alonso

Alvaro Alonso

63

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Martin G Larson

Martin G Larson

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Ramachandran S. Vasan

Ramachandran S Vasan

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Jerome I Rotter

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Jerome I Rotter

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Man Li

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Tamara B. Harris

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Tamara B Harris

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Jonathan D Smith

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Albert Hofman

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Albert Hofman

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Lenore J Launer

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Bruce M Psaty

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Edward Lakatta

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Susan R Heckbert

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Joshua C Bis

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Jacqueline C M Witteman

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Jacqueline C M Witteman

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H-Erich Wichmann

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Renate B Schnabel

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Patrick T Ellinor

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Steven A Lubitz

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Thomas J Wang

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Bruno H C Stricker

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Kenneth Rice

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Kristin D Marciante

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Dan E Arking

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Kirill V Tarasov

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Moritz F Sinner

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Germaine C Verwoert

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W H Linda Kao

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Samer S Najjar

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Georg B Ehret

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Elsayed Z Soliman

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Arne Pfeufer

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Charlotte van Noord

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Nona Sotoodehnia

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Britt M Beckmann

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Jared W Magnani

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Mina K Chung

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David R Van Wagoner

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Aravinda Chakravarti

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Siegfried Perz

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Stefan Kääb

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Martina Müller-Nurasyid

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Martina Müller

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Wiebke Sauter

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Daniel Levy

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John Barnard

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language of work or name

English

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publication date

10 January 2010

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29 July 2017

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volume

42

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issue

2

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page(s)

153-159

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describes a project that uses

29 July 2017

genome-wide association study

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Common variants in KCNN3 are associated with lone atrial fibrillation

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Long-term outcomes in individuals with prolonged PR interval or first-degree atrioventricular block

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Common variants at ten loci influence QT interval duration in the QTGEN Study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Ethnic distribution of ECG predictors of atrial fibrillation and its impact on understanding the ethnic distribution of ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

A comprehensive evaluation of SNP genotype imputation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Tbx3 is required for outflow tract development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Cardiac sodium channel overlap syndromes: different faces of SCN5A mutations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

The Rotterdam Study: objectives and design update

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Variants conferring risk of atrial fibrillation on chromosome 4q25.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Heritability of cardiovascular and personality traits in 6,148 Sardinians

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

A haplotype map of the human genome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

KORA-gen--resource for population genetics, controls and a broad spectrum of disease phenotypes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Function follows form: cardiac conduction system defects in Nkx2-5 mutation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Caveolae and caveolins in the cardiovascular system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

The transcription factors L-Sox5 and Sox6 are essential for cartilage formation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

Genomic control for association studies

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

A tetrodotoxin-resistant voltage-gated sodium channel from human dorsal root ganglia, hPN3/SCN10A

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

4 July 2018

Ulnar-mammary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

The Cardiovascular Health Study: design and rationale

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

The non-synonymous coding IKr-channel variant KCNH2-K897T is associated with atrial fibrillation: results from a systematic candidate gene-based analysis of KCNH2 (HERG)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: Design, Recruitment, and Initial Examination

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850197

C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation

30 October 2018

1 reference

12 December 2020

Monophasic action potential and sinus rhythm stability after conversion of atrial fibrillation

1 reference

12 December 2020

Variability of heart rate, P-R, QRS and Q-T durations in twins

1 reference

12 December 2020

Genetic factors in the electrocardiogram and heart rate of twins reared apart and together

1 reference

12 December 2020

A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation

1 reference

12 December 2020

Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study

1 reference

12 December 2020

The Diagnostic Performance of Computer Programs for the Interpretation of Electrocardiograms

1 reference

7 January 2021

A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization

1 reference

7 January 2021

A genotype calling algorithm for affymetrix SNP arrays.

1 reference

7 January 2021

1 reference

7 January 2021

Imputation-based analysis of association studies: candidate regions and quantitative traits

1 reference

7 January 2021

Family-based association tests for genomewide association scans

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG.517

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29 July 2017

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29 July 2017

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