Targeting chelatable iron as a therapeutic modality in Parkinson's disease (Q33768106)

29 July 2017

title

Targeting chelatable iron as a therapeutic modality in Parkinson's disease (English)

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29 July 2017

1 reference

4

Jérome Kluza

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Philippe Marchetti

Philippe Marchetti

28

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David Devos

David Devos

1

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Jean-Christophe Corvol

Jean-Christophe Corvol

23

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Marcel Leist

Marcel Leist

25

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Luc Defebvre

27

Luc Defebvre

1 reference

29 July 2017

Caroline Moreau

2

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29 July 2017

Jean Christophe Devedjian

3

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29 July 2017

Maud Petrault

5

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29 July 2017

Charlotte Laloux

6

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Aurélie Jonneaux

7

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29 July 2017

Gilles Ryckewaert

8

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29 July 2017

Guillaume Garçon

9

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Nathalie Rouaix

10

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29 July 2017

Alain Duhamel

11

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29 July 2017

Patrice Jissendi

12

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29 July 2017

Kathy Dujardin

13

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29 July 2017

Florent Auger

14

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29 July 2017

Laura Ravasi

15

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29 July 2017

Lucie Hopes

16

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29 July 2017

Guillaume Grolez

17

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29 July 2017

Wance Firdaus

18

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29 July 2017

Bernard Sablonnière

19

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Isabelle Strubi-Vuillaume

20

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Noel Zahr

21

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Alain Destée

22

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29 July 2017

Dominik Pöltl

24

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Christian Rose

26

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29 July 2017

Z Ioav Cabantchik

29

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29 July 2017

Régis Bordet

30

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29 July 2017

publication date

6 February 2014

1 reference

Antioxidants & Redox Signaling

29 July 2017

published in

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29 July 2017

volume

21

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29 July 2017

issue

2

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29 July 2017

page(s)

195-210

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Iron metabolism in the CNS: implications for neurodegenerative diseases

29 July 2017

cites work

1 reference

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Chronic intranasal deferoxamine ameliorates motor defects and pathology in the α-synuclein rAAV Parkinson's model.

22 June 2018

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Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia

22 June 2018

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X-ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons

22 June 2018

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Does structural neuroimaging reveal a disturbance of iron metabolism in Parkinson's disease? Implications from MRI and TCS studies

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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On improvement in ejection fraction with iron chelation in thalassemia major and the risk of future heart failure

22 June 2018

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The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention

22 June 2018

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A pilot trial of deferiprone for neurodegeneration with brain iron accumulation

22 June 2018

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Combined R2* and diffusion tensor imaging changes in the substantia nigra in Parkinson's disease

22 June 2018

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Mitochondrial mayhem: the mitochondrion as a modulator of iron metabolism and its role in disease

22 June 2018

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A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes

22 June 2018

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Oxidation Chemistry of Catecholamines and Neuronal Degeneration: An Update

22 June 2018

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Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line.

22 June 2018

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Profile of altered brain iron acquisition in restless legs syndrome

22 June 2018

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The potential application of iron chelators for the treatment of neurodegenerative diseases.

22 June 2018

1 reference

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Iron chelation and neuroprotection in neurodegenerative diseases

22 June 2018

1 reference

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Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal

22 June 2018

1 reference

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Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

22 June 2018

1 reference

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Combined therapy with idebenone and deferiprone in patients with Friedreich's ataxia.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Mitochondrial iron metabolism and its role in neurodegeneration.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Iron redistribution as a therapeutic strategy for treating diseases of localized iron accumulation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Study of brain anatomy with high-field MRI: recent progress

22 June 2018

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Iron regulatory proteins: from molecular mechanisms to drug development

22 June 2018

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Neuroprotective multifunctional iron chelators: from redox-sensitive process to novel therapeutic opportunities

22 June 2018

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Deferiprone chelation therapy for thalassemia major

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Anemia or low hemoglobin levels preceding Parkinson disease: a case-control study.

22 June 2018

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A double-blind, delayed-start trial of rasagiline in Parkinson's disease

22 June 2018

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Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease

22 June 2018

1 reference

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Glutathione--a review on its role and significance in Parkinson's disease

22 June 2018

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22 June 2018

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Regulation of iron acquisition and storage: consequences for iron-linked disorders

22 June 2018

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Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Non-transferrin-bound iron reaches mitochondria by a chelator-inaccessible mechanism: biological and clinical implications.

22 June 2018

1 reference

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Ferritin and ferritin isoforms I: Structure-function relationships, synthesis, degradation and secretion

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Intracellular labile iron.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Magnetic resonance imaging measurement of iron overload

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Oxidative stress and neurodegeneration: where are we now?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Timing of treatment initiation in Parkinson's disease: a need for reappraisal?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Dunkerque City air pollution particulate matter-induced cytotoxicity, oxidative stress and inflammation in human epithelial lung cells (L132) in culture

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Relaxation induced by ferritin: a better understanding for an improved MRI iron quantification

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Iron, brain ageing and neurodegenerative disorders

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Iron misregulation in the brain: a primary cause of neurodegenerative disorders

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Iron metabolism and mitochondrial abnormalities in Friedreich ataxia

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

A review of fluorescence methods for assessing labile iron in cells and biological fluids

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Polycyclic aromatic hydrocarbon coated onto Fe(2)O(3) particles: assessment of cellular membrane damage and antioxidant system disruption in human epithelial lung cells (L132) in culture

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Mitochondrial Ca2 transients in cardiac myocytes during the excitation-contraction cycle: effects of pacing and hormonal stimulation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

The possible role of iron in the etiopathology of Parkinson's disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Inhibition of catechol-O-methyltransferase (COMT) as well as tyrosine and tryptophan hydroxylase by the orally active iron chelator, 1,2-dimethyl-3-hydroxypyridin-4-one (L1, CP20), in rat brain in vivo

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Increased nigral iron content in postmortem parkinsonian brain

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Cellular distribution of transferrin, ferritin, and iron in normal and aged human brains

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Differential susceptibility to the PPAR-γ agonist pioglitazone in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 6-hydroxydopamine rodent models of Parkinson's disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

H‐ferritin is the major source of iron for oligodendrocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Magnetic resonance imaging markers of Parkinson's disease nigrostriatal signature

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

MRI assessment of basal ganglia iron deposition in Parkinson's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Selective iron chelation in Friedreich ataxia: biologic and clinical implications

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Increased sensitivity of striatal dopamine release to H2O2 upon chronic rotenone treatment

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

High-performance liquid chromatography/tandem mass spectrometry assay for the determination of 1-methyl-4-phenyl pyridinium (MPP ) in brain tissue homogenates

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Modulation of somatodendritic dopamine release by endogenous H(2)O(2): susceptibility in substantia nigra but resistance in VTA.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060813

Biomonitoring of the adverse effects induced by the chronic exposure to lead and cadmium on kidney function: usefulness of alpha-glutathione S-transferase

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24251381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson's disease after peripheral administration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24251381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24251381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/ARS.2013.5593

1 reference

29 July 2017

1 reference

29 July 2017

1 reference