Epigenetic changes in the myelodysplastic syndrome. (Q33767309)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

review article

1 reference

title

Epigenetic changes in the myelodysplastic syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Jean-Pierre Issa

series ordinal

1

1 reference

PubMed publication ID

20359628

29 July 2017

publication date

1 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

Hematology / Oncology Clinics of North America

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

317-330

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes

29 January 2020

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14 July 2018

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14 July 2018

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14 July 2018

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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

14 July 2018

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14 July 2018

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Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation

14 July 2018

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Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

14 July 2018

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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

14 July 2018

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Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome

14 July 2018

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Epigenetics in human disease and prospects for epigenetic therapy

14 July 2018

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Epigenetic changes in colorectal cancer.

14 July 2018

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The nucleosome: from genomic organization to genomic regulation

14 July 2018

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Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains

14 July 2018

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Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

14 July 2018

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Gene silencing in cancer in association with promoter hypermethylation

14 July 2018

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MLL-rearranged leukemias: insights from gene expression profiling

14 July 2018

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Aberrant methylation of DAP-kinase in therapy-related acute myeloid leukemia and myelodysplastic syndromes

14 July 2018

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14 July 2018

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Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia

14 July 2018

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Molecular mechanisms of myelodysplastic syndrome

14 July 2018

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The molecular pathogenesis of acute promyelocytic leukaemia: implications for the clinical management of the disease

14 July 2018

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14 July 2018

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DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias.

14 July 2018

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Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Active genes are tri-methylated at K4 of histone H3

14 July 2018

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DNA methylation in cancer: too much, but also too little

14 July 2018

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14 July 2018

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14 July 2018

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Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

14 July 2018

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

14 July 2018

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DNA methylation patterns and epigenetic memory

14 July 2018

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Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily

14 July 2018

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A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

14 July 2018

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Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

14 July 2018

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Translating the Histone Code

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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DNA methyltransferase Dnmt1 associates with histone deacetylase activity

14 July 2018

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14 July 2018

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14 July 2018

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CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.

14 July 2018

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

14 July 2018

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Cancer epigenetics comes of age

14 July 2018

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

14 July 2018

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Role of DNA 5-methylcytosine transferase in cell transformation by fos

14 July 2018

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DNA hypomethylation leads to elevated mutation rates

14 July 2018

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

14 July 2018

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Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia.

14 July 2018

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X-chromosome inactivation in mammals

14 July 2018

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Alterations in DNA methylation: a fundamental aspect of neoplasia

14 July 2018

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DNA demethylation and pericentromeric rearrangements of chromosome 1

14 July 2018

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International scoring system for evaluating prognosis in myelodysplastic syndromes

14 July 2018

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Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

14 July 2018

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Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

14 July 2018

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Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

14 July 2018

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Role for DNA methylation in genomic imprinting

14 July 2018

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Hypomethylation of DNA: a possible nongenotoxic mechanism underlying the role of cell proliferation in carcinogenesis

14 July 2018

1 reference

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

14 July 2018

1 reference

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Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway

14 July 2018

1 reference

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Gametic imprinting in mammals

14 July 2018

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

14 July 2018

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Cellular differentiation, cytidine analogs and DNA methylation

14 July 2018

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DNA methylation and gene activity

14 July 2018

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Altering gene expression with 5-azacytidine

14 July 2018

1 reference

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DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture

14 July 2018

1 reference

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Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene

14 July 2018

1 reference

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Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

14 July 2018

1 reference

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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

30 October 2018

1 reference

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Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome

30 October 2018

1 reference

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Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome

30 October 2018

1 reference

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RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.

30 October 2018

1 reference

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Loss of the tumor suppressor p15Ink4b enhances myeloid progenitor formation from common myeloid progenitors.

30 October 2018

1 reference

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Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients

30 October 2018

1 reference

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Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome

30 October 2018

1 reference

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Aberrant methylation of the negative regulators RASSFIA, SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemia.

30 October 2018

1 reference

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Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid

30 October 2018

1 reference

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Comment on "Chromosomal instability and tumors promoted by DNA hypomethylation" and "Induction of tumors in nice by genomic hypomethylation".

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

DNA methylation differences associated with tumor tissues identified by genome scanning analysis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

Cell cycle-dependent regulation of eukaryotic DNA methylase level.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848959

Hypermethylation of the calcitonin gene in the myelodysplastic syndromes

30 October 2018

1 reference

12 December 2020

Increased cytosine DNA-methyltransferase activity during colon cancer progression

1 reference

12 December 2020

Hypermethylation of the p15INK4B gene in myelodysplastic syndromes

1 reference

12 December 2020

Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression

1 reference

12 December 2020

Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: clinicopathological and karyotypic associations

1 reference

12 December 2020

Effect of cytarabine and decitabine in combination in human leukemic cell lines

1 reference

12 December 2020

Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromes

1 reference

12 December 2020

Methylation of the p15(INK4B) gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation

1 reference

12 December 2020

10.1016/J.HOC.2010.02.007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20359628 AND SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

20359628

1 reference