High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia. (Q33763739)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15655112 AND SRC:MED&resulttype=core&format=json

7 January 2020

title

High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia (English)

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7 January 2020

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3

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7 January 2020

4

Guy Sauvageau

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7 January 2020

author name string

Janet Bijl

series ordinal

1

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7 January 2020

Martin Sauvageau

series ordinal

2

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7 January 2020

publication date

1 January 2005

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7 January 2020

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7 January 2020

volume

19

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7 January 2020

issue

2

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7 January 2020

page(s)

224-233

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E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice

7 January 2020

cites work

1 reference

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

22 June 2018

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Global down-regulation of HOX gene expression in PML-RARalpha acute promyelocytic leukemia identified by small-array real-time PCR.

22 June 2018

1 reference

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Gradient of E2A activity in B-cell development

22 June 2018

1 reference

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HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation

22 June 2018

1 reference

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HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis

22 June 2018

1 reference

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Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation

22 June 2018

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The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells

22 June 2018

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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

22 June 2018

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Stage-specific expression of polycomb group genes in human bone marrow cells

22 June 2018

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Oncogenic Transcription Factors in the Human Acute Leukemias

22 June 2018

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Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia

22 June 2018

1 reference

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Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

22 June 2018

1 reference

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DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation.

22 June 2018

1 reference

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Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen

22 June 2018

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E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice

22 June 2018

1 reference

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Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

22 June 2018

1 reference

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Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

22 June 2018

1 reference

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Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene

22 June 2018

1 reference

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Differential expression of homeobox genes in functionally distinct CD34 subpopulations of human bone marrow cells

22 June 2018

1 reference

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Stromal cell independent growth of bipotent B cell--macrophage precursors from murine fetal liver

22 June 2018

1 reference

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Pre-B cell leukemia associated with chromosome translocation 1;19.

22 June 2018

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A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545883

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545883

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545883

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

22 June 2018

1 reference

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Large-scale identification of novel potential disease loci in mouse leukemia applying an improved strategy for cloning common virus integration sites

22 June 2018

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High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

30 October 2018

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AP-1 complex is effector of Hox-induced cellular proliferation and transformation.

30 October 2018

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A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545883

Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545883

Chromosomal translocations in human cancer.

30 October 2018

1 reference

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Oncoprotein E2A-Pbx1 immortalizes a myeloid progenitor in primary marrow cultures without abrogating its factor-dependence.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545883

Identification and characterization of collaborating oncogenes in compound mutant mice

30 October 2018

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12 December 2020

Cooperative interactions between PBX, PREP, and HOX proteins modulate the activity of the alpha 2(V) collagen (COL5A2) promoter

1 reference

12 December 2020

New genes involved in cancer identified by retroviral tagging

1 reference

12 December 2020

New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia

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12 December 2020

Long-term culture of murine bone marrow precursors of B lymphocytes

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12 December 2020

Identifiers

DOI

10.1101/GAD.1268505

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15655112 AND SRC:MED&resulttype=core&format=json

7 January 2020

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7 January 2020

PubMed publication ID

15655112

1 reference