Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice (Q33749640)

24771859

29 July 2017

title

Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice (English)

1 reference

alternative mRNA splicing, via spliceosome

29 July 2017

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771859 AND SRC:MED&resulttype=core&format=json

1 June 2020

Yi-Jou Huang

6

1 reference

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1 June 2020

Daniel G Tenen

7

1 reference

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1 June 2020

Yukiko Komeno

1

1 reference

ORCID Public Data File 2021

author name string

Ming Yan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771859 AND SRC:MED&resulttype=core&format=json

1 June 2020

Kentson Lam

4

1 reference

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1 June 2020

Miao-Chia Lo

5

1 reference

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1 June 2020

James R Downing

8

1 reference

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1 June 2020

Dong-Er Zhang

9

1 reference

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1 June 2020

language of work or name

English

0 references

publication date

25 April 2014

1 reference

29 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771859 AND SRC:MED&resulttype=core&format=json

1 June 2020

volume

123

1 reference

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1 June 2020

issue

24

1 reference

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1 June 2020

page(s)

3760-3769

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771859 AND SRC:MED&resulttype=core&format=json

Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration.

1 June 2020

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RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells

21 June 2018

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Novel function of the unique N-terminal region of RUNX1c in B cell growth regulation

21 June 2018

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RUNX family: Regulation and diversification of roles through interacting proteins

21 June 2018

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New insights into the role of Runx1 in epithelial stem cell biology and pathology

21 June 2018

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Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

21 June 2018

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Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome

21 June 2018

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A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation

21 June 2018

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Control of alternative splicing by forskolin through hnRNP K during neuronal differentiation

21 June 2018

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Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis

21 June 2018

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis

21 June 2018

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Expansion of functionally defined mouse hematopoietic stem and progenitor cells by a short isoform of RUNX1/AML1.

21 June 2018

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Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma

21 June 2018

1 reference

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Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells

21 June 2018

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The core binding factor CBF negatively regulates skeletal muscle terminal differentiation

21 June 2018

1 reference

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CHIP functions an E3 ubiquitin ligase of Runx1.

21 June 2018

1 reference

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A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis

21 June 2018

1 reference

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Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity

21 June 2018

1 reference

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Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1

21 June 2018

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AML1/RUNX1 phosphorylation by cyclin-dependent kinases regulates the degradation of AML1/RUNX1 by the anaphase-promoting complex

21 June 2018

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The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3.

21 June 2018

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Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

21 June 2018

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AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

21 June 2018

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Role of RUNX1 in adult hematopoiesis: analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression

21 June 2018

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AML-1A and AML-1B regulation of MIP-1alpha expression in multiple myeloma.

21 June 2018

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Expression and function of a stem cell promoter for the murine CBFalpha2 gene: distinct roles and regulation in natural killer and T cell development.

21 June 2018

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Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

21 June 2018

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Identification and expression of a novel 3'-exon of mouse Runx1/Pebp2alphaB/Cbfa2/AML1 gene

21 June 2018

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Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains

21 June 2018

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Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions

21 June 2018

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 June 2018

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The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor

21 June 2018

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PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials

21 June 2018

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Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)

21 June 2018

1 reference

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Alternative splicing and genomic structure of theAML1gene involved in acute myeloid leukemia

21 June 2018

1 reference

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Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEBP2.

21 June 2018

1 reference

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t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

A novel recurrent AML1-ETO fusion: tight in vivo association with BCR-ABL1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Runx1 promotes neuronal differentiation in dorsal root ganglion.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Nonredundant roles for Runx1 alternative promoters reflect their activity at discrete stages of developmental hematopoiesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Overexpression of an isoform of AML1 in acute leukemia and its potential role in leukemogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Identification of a novel splice variant of AML1b in ovarian cancer patients conferring loss of wild-type tumor suppressive functions.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Regulation of RUNX1/AML1 during the G2/M transition.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Lineage- and stage-specific expression of runt box polypeptides in primitive and definitive hematopoiesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055923

Expression of RUNX1 isoforms and its target gene BLK in childhood acute lymphoblastic leukemia

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24771859

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The expression pattern of the AML1 gene in non-Hodgkin's B-cell lymphomas and normal B lymphocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24771859

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24771859

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2013-08-521252

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771859 AND SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771859 AND SRC:MED&resulttype=core&format=json

1 June 2020

24771859

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771859 AND SRC:MED&resulttype=core&format=json