Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase (Q33744544)

29 July 2017

title

Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase (English)

1 reference

29 July 2017

S Baekkeskov

7

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Jeffrey L. Noebels

4

object named as

J L Noebels

1 reference

29 July 2017

S F Kash

1

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29 July 2017

R S Johnson

2

1 reference

29 July 2017

L H Tecott

3

1 reference

29 July 2017

R D Mayfield

5

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29 July 2017

D Hanahan

6

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29 July 2017

language of work or name

English

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publication date

1 December 1997

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

94

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29 July 2017

issue

25

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29 July 2017

page(s)

14060-14065

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Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase

29 July 2017

cites work

1 reference

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Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior

21 June 2018

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Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alpha

21 June 2018

1 reference

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Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures

21 June 2018

1 reference

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Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets.

21 June 2018

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Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat.

21 June 2018

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The exon-intron organization of the genes (GAD1 and GAD2) encoding two human glutamate decarboxylases (GAD67 and GAD65) suggests that they derive from a common ancestral GAD.

21 June 2018

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Genetic epilepsy model derived from common inbred mouse strains

21 June 2018

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21 June 2018

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Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

21 June 2018

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Limbic epilepsy in transgenic mice carrying a Ca2 /calmodulin-dependent kinase II alpha-subunit mutation

21 June 2018

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Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6.

21 June 2018

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Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus.

21 June 2018

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Mapping patterns of c-fos expression in the central nervous system after seizure

21 June 2018

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21 June 2018

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Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome

21 June 2018

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Two genes encode distinct glutamate decarboxylases

21 June 2018

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GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

21 June 2018

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Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions.

21 June 2018

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Regulatory properties of brain glutamate decarboxylase (GAD): the apoenzyme of GAD is present principally as the smaller of two molecular forms of GAD in brain

21 June 2018

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Glutamate decarboxylases in nonneural cells of rat testis and oviduct: differential expression of GAD65 and GAD67.

21 June 2018

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

21 June 2018

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Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain

21 June 2018

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High Concentration of GABA and High Glutamate Decarboxylase Activity in Rat Pancreatic Islets and Human Insulinoma

21 June 2018

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Different distributions of GAD65 and GAD67 mRNAs suggest that the two glutamate decarboxylases play distinctive functional roles.

21 June 2018

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Regional differences in cofactor saturation of glutamate decarboxylase (GAD) in discrete brain nuclei of the rat. Effect of repeated administration of haloperidol on GAD activity in the substantia nigra

21 January 2018

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Differential expression of glutamic acid decarboxylase in rat and human islets

21 January 2018

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21 January 2018

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New seizure frequency QTL and the complex genetics of epilepsy in EL mice

21 January 2018

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Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures.

21 January 2018

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Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble

30 October 2018

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Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

30 October 2018

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21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/9391152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pattern and time course of immediate early gene expression in rat brain following acute stress

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PubMed

https://pubmed.ncbi.nlm.nih.gov/9391152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Familial temporal lobe epilepsy: a common disorder identified in twins

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PubMed

https://pubmed.ncbi.nlm.nih.gov/9391152

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1073/PNAS.94.25.14060

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference