Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis (Q33741241)

29 July 2017

title

Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis (English)

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29 July 2017

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9

Ludger Schöls

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29 July 2017

10

Ingemar Björkhem

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29 July 2017

1

Rebecca Schüle

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29 July 2017

Han-Xiang Deng

3

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author name string

Teepu Siddique

2

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29 July 2017

Yi Yang

4

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29 July 2017

Sandra Donkervoort

5

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29 July 2017

Magnus Hansson

6

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29 July 2017

Ricardo E Madrid

7

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29 July 2017

Nailah Siddique

8

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29 July 2017

publication date

7 October 2009

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Journal of Lipid Research

29 July 2017

published in

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29 July 2017

volume

51

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29 July 2017

issue

4

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29 July 2017

page(s)

819-823

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CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions

29 July 2017

cites work

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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

14 July 2018

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14 July 2018

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Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration

14 July 2018

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Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway

14 July 2018

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Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain.

14 July 2018

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The enzymes, regulation, and genetics of bile acid synthesis

14 July 2018

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Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis

14 July 2018

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Oxysterols: friends, foes, or just fellow passengers?

14 July 2018

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The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

14 July 2018

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Cholesterol metabolism in the brain

14 July 2018

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Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

14 July 2018

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Oxysterols: modulators of cholesterol metabolism and other processes

14 July 2018

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Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease

14 July 2018

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Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

14 July 2018

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Serum concentrations of ursodeoxycholic acid in portal venous and systemic venous blood of fasting humans as determined by isotope dilution-mass spectrometry

14 July 2018

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Linkage of 'pure' autosomal recessive familial spastic paraplegia to chromosome 8 markers and evidence of genetic locus heterogeneity.

14 July 2018

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Analysis of CYP7B1 in non-consanguineous cases of hereditary spastic paraplegia

21 January 2018

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CYP7B1 mutations in pure and complex forms of hereditary spastic paraplegia type 5.

21 January 2018

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Neonatal cholestatic liver disease in an Asian patient with a homozygous mutation in the oxysterol 7alpha-hydroxylase gene

21 January 2018

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Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid

21 January 2018

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Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?

21 January 2018

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Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization

21 January 2018

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Diagnostic use of cerebral and extracerebral oxysterols

21 January 2018

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Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.

21 January 2018

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Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

21 January 2018

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Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers.

21 January 2018

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21 January 2018

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Oxysterols induce interleukin-1beta production in human macrophages

21 January 2018

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Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes

21 January 2018

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24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A).

21 January 2018

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Assay of the major bile acids in serum by isotope dilution-mass spectrometry

30 October 2018

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Distal axonopathy in an alsin-deficient mouse model

30 October 2018

1 reference

Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry

21 January 2018

1 reference

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Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production

10 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19812052

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M002543

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29 July 2017

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29 July 2017

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