The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase (Q33741157)

29 July 2017

title

The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase (English)

1 reference

29 July 2017

5

Keith C Bible

1 reference

29 July 2017

Jennifer D Tibodeau

1

1 reference

29 July 2017

Linda M Benson

series ordinal

2

1 reference

29 July 2017

Crescent R Isham

series ordinal

3

1 reference

29 July 2017

Whyte G Owen

series ordinal

4

1 reference

29 July 2017

publication date

1 May 2009

1 reference

Antioxidants & Redox Signaling

29 July 2017

published in

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29 July 2017

volume

11

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29 July 2017

issue

5

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29 July 2017

page(s)

1097-1106

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Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress

29 July 2017

cites work

1 reference

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Selective inactivation of glutaredoxin by sporidesmin and other epidithiopiperazinediones

14 July 2018

1 reference

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Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity

14 July 2018

1 reference

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Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase

14 July 2018

1 reference

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The thioredoxin reductase/thioredoxin system: novel redox targets for cancer therapy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress

14 July 2018

1 reference

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ROS stress in cancer cells and therapeutic implications

14 July 2018

1 reference

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Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin reductase as a pathophysiological factor and drug target

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin reductase two modes of catalysis have evolved

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Physiological functions of thioredoxin and thioredoxin reductase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Purification and characterization of ACR2p, the Saccharomyces cerevisiae arsenate reductase.

14 July 2018

1 reference

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Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Mitochondria can import artificial precursor proteins containing a branched polypeptide chain or a carboxy-terminal stilbene disulfonate

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Mechanisms of inhibition of the thioredoxin growth factor system by antitumor 2-imidazolyl disulfides

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842135

Thioredoxin expression is associated with lymph node status and prognosis in early operable non-small cell lung cancer

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18999987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/ARS.2008.2318

1 reference

release_kp3mmx67m5bznbq4yq77vyvn2i

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kp3mmx67m5bznbq4yq77vyvn2i

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

2842135

1 reference

29 July 2017

1 reference