Pharmacology and metabolism of alcohol, including its metabolic effects and interactions with other drugs (Q33738727)

29 July 2017

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title

Pharmacology and metabolism of alcohol, including its metabolic effects and interactions with other drugs (English)

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29 July 2017

1 reference

Lieber CS

1

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29 July 2017

Abittan CS

series ordinal

2

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29 July 2017

publication date

1 July 1999

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29 July 2017

published in

Clinics in Dermatology

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29 July 2017

volume

17

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29 July 2017

issue

4

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29 July 2017

page(s)

365-379

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Ethanol causes acute inhibition of carbohydrate, fat, and protein oxidation and insulin resistance

29 July 2017

cites work

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7 January 2021

Gastric emptying and gastrointestinal absorption of alcohol ingested with a meal

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7 January 2021

First pass metabolism of ethanol: an important determinant of blood levels after alcohol consumption

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7 January 2021

Human gastric alcohol dehydrogenase: its inhibition by H2-receptor antagonists, and its effect on the bioavailability of ethanol

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7 January 2021

Purification and partial amino acid sequence of a high-activity human stomach alcohol dehydrogenase

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7 January 2021

Alcohol dehydrogenase of class IV (sigma sigma-ADH) from human stomach. cDNA sequence and structure/function relationships

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Molecular cloning of human class IV alcohol dehydrogenase cDNA

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Molecular cloning and chromosomal localization of the ADH7 gene encoding human class IV (sigma) ADH.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Upstream structure of human ADH7 gene and the organ distribution of its expression

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Metabolism of ethanol in rat gastric cells and its inhibition by cimetidine

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Metabolism of alcohol by human gastric cells: relation to first-pass metabolism

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

First-pass gastric mucosal metabolism of ethanol is negligible in the rat

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

First-pass metabolism of ethanol: an overview

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

First-pass metabolism of ethanol is predominantly gastric

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Aspirin increases blood alcohol concentrations in humans after ingestion of ethanol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effects of cimetidine on gastric alcohol dehydrogenase activity and blood ethanol levels

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Cimetidine Inhibition of Human Gastric and Liver Alcohol Dehydrogenase Isoenzymes: Identification of Inhibitor Complexes by Kinetics and Molecular Modeling

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Ranitidine increases the bioavailability of imbibed alcohol by accelerating gastric emptying

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Significant increase of blood alcohol by cimetidine after repetitive drinking of small alcohol doses

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Short report: the effect of ranitidine on the post-prandial absorption of a low dose of alcohol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Drinking and flying--the problem of alcohol use by pilots

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Skills performance at low blood alcohol levels

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Lack of alcohol dehydrogenase isoenzyme activities in the stomach of Japanese subjects

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Ethnic differences in gastric sigma-alcohol dehydrogenase activity and ethanol first-pass metabolism

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hepatic glutathione determination after ethanol administration in rat: evidence of the first-pass metabolism of ethanol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Glycine prevents alcohol-induced liver injury by decreasing alcohol in the rat stomach

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Ascitic cirrhosis in relation to alcohol consumption

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Do women develop alcoholic brain damage more readily than men?

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Human gastric alcohol dehydrogenase activity: effect of age, sex, and alcoholism

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effects of fasting and chronic alcohol consumption on the first-pass metabolism of ethanol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effect of concentration of ingested ethanol on blood alcohol levels

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Comparison of blood alcohol concentrations after beer and whiskey

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Role of cysteine proteases and protease inhibitors in gastric mucosal damage induced by ethanol or ammonia in the rat.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Chronic alcoholic gastritis. Roles of alcohol and Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

On the Role of Alcohol Dehydrogenase in omega-Oxidation of Fatty Acids

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Genetic factors in alcohol metabolism and alcoholism

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Alcohol and the liver: 1994 update.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Ethanol oxidation by hepatic microsomes: adaptive increase after ethanol feeding

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Implication of free radical mechanisms in ethanol-induced cellular injury

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Stable expression of human cytochrome P4502E1 in HepG2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effect of chronic ethanol administration on bromobenzene liver toxicity in the rat

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Influence of alcohol, dithiocarb and ( )-catechin on the hepatotoxicity and metabolism of vinylidene chloride in rats

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Interaction of ethanol with enflurane metabolism and toxicity: role of P450IIE1.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Assessment of the role of non-ADH ethanol oxidation in vivo and in hepatocytes from deermice

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Kinetic studies on benzene metabolism in rat liver--possible presence of three forms of benzene metabolizing enzymes in the liver

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hepatic vitamin A depletion after chronic ethanol consumption in baboons and rats

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Acetaminophen Toxicity in an Urban County Hospital

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

1 reference

7 January 2021

Enhanced pulmonary and intestinal activation of procarcinogens and mutagens after chronic ethanol consumption in the rat.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Ethanol and intestinal carcinogenesis in the rat

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Immunohistochemical localization of ethanol-inducible P450IIE1 in the rat alimentary tract

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Ethanol-induced hyperuricemia: evidence for increased urate production by activation of adenine nucleotide turnover

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

1 reference

7 January 2021

Properties of catalase. Catalysis of coupled oxidation of alcohols

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The steady state level of catalase compound I in isolated hemoglobin-free perfused rat liver

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Microsomal Ethanol Oxidizing System (MEOS): Current Status of Its Characterization and Its Role

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The Role of Alcohol Dehydrogenase in Microsomal Ethanol Oxidation and the Adaptive Increase in Ethanol Metabolism due to Chronic Treatment With Ethanol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Increased susceptibility of hepatic mitochondria to the toxicity of acetaldehyde after chronic ethanol consumption

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Presence of nonoxidative ethanol metabolism in human organs commonly damaged by ethanol abuse

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Acetaldehyde Oxidation by Hepatic Mitochondria: Decrease After Chronic Ethanol Consumption

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effect of abstinence on the blood acetaldehyde response to a test dose of alcohol in alcoholics

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

In vitro and in vivo inhibitory effect of ethanol and acetaldehyde on O6-methylguanine transferase

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Impaired oxygen utilization. A new mechanism for the hepatotoxicity of ethanol in sub-human primates

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease. Evidence of lipid peroxidation

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Chronic ethanol consumption alters rat liver plasma membranes and potentiates release of alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hepatic Phosphatidylethanolamine Methyltransferase Activity Is Decreased by Ethanol and Increased by Phosphatidylcholine

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Polyenylphosphatidylcholine prevents carbon tetrachloride-induced lipid peroxidation while it attenuates liver fibrosis

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Application of a high performance liquid chromatography method for screening of aldehyde dehydrogenase isozyme deficiency in hair roots from different ethnic groups

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Isoenzymes of Aldehyde Dehydrogenase in Human Lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Cutaneous vasomotor sensitivity to ethanol and acetaldehyde: subtypes of alcohol-flushing response among Chinese

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Sex hormone binding globulin: origin, function and clinical significance

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Mechanism of feminization in male patients with non-alcoholic liver cirrhosis: role of sex hormone-binding globulin

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The skin-liver connection

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hematologic effects of acute and chronic alcohol abuse.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The finger-nails in chronic hypoalbuminaemia; a new physical sign

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

1 reference

7 January 2021

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

1 reference

7 January 2021

Zinc metabolism in hepatic dysfunction. I. Serum zinc concentrations in Laënnec's cirrhosis and their validation by sequential analysis

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Estimated hepatic blood flow in the dog; effect of ethyl alcohol on it, renal blood flow, cardiac output and arterial pressure

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effect of intravenous infusions of ethyl alcohol on estimated hepatic blood flow in man.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The effect of a single oral dose of ethanol on hepatic blood flow in man

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The influence of fructose on the kinetics of alcohol elimination in man

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effect of intravenous infusions of ethanol upon estimated hepatic blood flow in man

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

THE EFFECT OF ETHANOL UPON SYSTEMIC AND HEPATIC BLOOD FLOW IN MAN

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Increased Hepatic Oxygenation following Ethanol Administration in the Baboon

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Mechanism for selective perivenular hepatotoxicity of ethanol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hepatic venous oxygen content in alcoholic cirrhosis and non-cirrhotic alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Ethanol-induced increase in portal hepatic blood flow: interference by anesthetic agents

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The liver in hypothermia

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The effect of cooling on liver function in cats

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The effect of slight hypothermia on liver function as measured by the elimination rate of ethanol, the hepatic uptake and excretion of indocyanine green and bile formation

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Diurnal variation in rate of alcohol metabolism

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Chronopharmacokinetics of ethanol. II. Circadian rhythm in rate of blood level decline in a single subject

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Circadian Variation of Ethanol Metabolism in Alcoholics*

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hepatic vitamin A depletion in alcoholic liver injury

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

NAD -dependent retinol dehydrogenase in liver microsomes

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Interaction of drugs and retinol.

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effects of Vitamin A on 3-Methylcholanthrene-Induced Squamous Metaplasias and Early Tumors in the Respiratory Tract of Rats 2

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Dietary habits and lung cancer risk

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Prospective study of alcohol consumption and cancer

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Alcohol Dehydrogenase as a Critical Mediator of Retinoic Acid Synthesis from Vitamin A in the Mouse Embryo ,

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Regional Restriction of Alcohol/Retinol Dehydrogenases along the Mouse Gastrointestinal Epithelium

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

A hypothetical mechanism for fetal alcohol syndrome involving ethanol inhibition of retinoic acid synthesis at the alcohol dehydrogenase step

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hypothesis: prenatal ethanol-induced birth defects and retinoic acid

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Hypervitaminosis A: a liver lover's lament

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Diet and esophageal cancer in Calvados (France).

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Vitamin A and other dietary factors in the etiology of esophageal cancer

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Nutritional epidemiology of cancer of the esophagus

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The toxicity of beta-carotene

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Interactions between alcohol and beta-carotene in patients with alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effect of alcohol consumption on plasma carotenoid concentrations in premenopausal women: a controlled dietary study

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Interaction of ethanol with beta-carotene: delayed blood clearance and enhanced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

β-Carotene beadlets potentiate hepatotoxicity of alcohol

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial

1 reference

https://api.crossref.org/works/10.1016/S0738-081X(99)50020-6

7 January 2021

10.1016/S0738-081X(99)00020-6

Identifiers

DOI

1 reference

29 July 2017

1 reference