Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver (Q33737640)

29 July 2017

title

Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver (English)

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29 July 2017

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8

Markus Grompe

1 reference

29 July 2017

Hiroyuki Nakai

1

1 reference

29 July 2017

Xiaolin Wu

2

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29 July 2017

Sally Fuess

3

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29 July 2017

Theresa A Storm

4

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29 July 2017

David Munroe

5

1 reference

29 July 2017

Eugenio Montini

6

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29 July 2017

Shawn M Burgess

7

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29 July 2017

Mark A Kay

9

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29 July 2017

publication date

1 March 2005

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29 July 2017

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29 July 2017

volume

79

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29 July 2017

issue

6

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29 July 2017

page(s)

3606-3614

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Adeno-associated virus vectors integrate at chromosome breakage sites

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

A gene atlas of the mouse and human protein-encoding transcriptomes

21 June 2018

1 reference

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RTCGD: retroviral tagged cancer gene database

21 June 2018

1 reference

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Transcription start regions in the human genome are favored targets for MLV integration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

AAV serotype 2 vectors preferentially integrate into active genes in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Packaging of human chromosome 19-specific adeno-associated virus (AAV) integration sites in AAV virions during AAV wild-type and recombinant AAV vector production.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Genetic fate of recombinant adeno-associated virus vector genomes in muscle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

HIV-1 integration in the human genome favors active genes and local hotspots

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

21 June 2018

1 reference

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Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Isolation of recombinant adeno-associated virus vector-cellular DNA junctions from mouse liver

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Adeno-associated virus vector integration junctions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Structural analysis of mouse rDNA: coincidence between nuclease hypersensitive sites, DNA curvature and regulatory elements in the intergenic spacer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Mapping of replication initiation sites in the mouse ribosomal gene cluster

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Enhancers for RNA polymerase I in mouse ribosomal DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Complete sequence of the 45-kb mouse ribosomal DNA repeat: analysis of the intergenic spacer☆

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Adeno-associated virus vectors under scrutiny

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Chromosomal effects of adeno-associated virus vector integration

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1075691

Looking into the safety of AAV vectors

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15731255

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The kinetics of rAAV integration in the liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15731255

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.79.6.3606-3614.2005

1 reference

29 July 2017

1 reference

29 July 2017

1 reference