Gla-rich protein is a potential new vitamin K target in cancer: evidences for a direct GRP-mineral interaction (Q33737404)

29 July 2017

title

Gla-rich protein is a potential new vitamin K target in cancer: evidences for a direct GRP-mineral interaction (English)

1 reference

29 July 2017

0 references

1 reference

Inês M Luís

6

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Marta S. Rafael

Marta S Rafael

3

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Carla S B Viegas

Carla S B Viegas

1

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Dina C. Simes

Dina C Simes

15

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Cees Vermeer

Cees Vermeer

14

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author name string

Marjolein Herfs

2

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29 July 2017

José L Enriquez

4

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29 July 2017

Alexandra Teixeira

5

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29 July 2017

Cynthia M R van 't Hoofd

7

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29 July 2017

Alexandre João

8

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29 July 2017

Vera L Maria

9

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29 July 2017

Sofia Cavaco

10

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29 July 2017

Ana Ferreira

11

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29 July 2017

Manuel Serra

12

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29 July 2017

Elke Theuwissen

13

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29 July 2017

language of work or name

English

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publication date

18 May 2014

1 reference

BioMed Research International

29 July 2017

published in

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29 July 2017

volume

2014

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29 July 2017

page(s)

340216

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Creative Commons Attribution 3.0 Unported

29 July 2017

copyright license

start time

1 January 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Ectopic mineralization disorders of the extracellular matrix of connective tissue: molecular genetics and pathomechanisms of aberrant calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Menaquinones, bacteria, and the food supply: the relevance of dairy and fermented food products to vitamin K requirements.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Proteomic Identification of a Novel Hsp90-Containing Protein–Mineral Complex Which Can Be Induced in Cells in Response to Massive Calcium Influx

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

The role of vitamin K in soft-tissue calcification

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Vitamin K: the effect on health beyond coagulation - an overview

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Microcalcifications in breast cancer: novel insights into the molecular mechanism and functional consequence of mammary mineralisation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Ucmaa (Grp-2) is required for zebrafish skeletal development. Evidence for a functional role of its glutamate γ-carboxylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Vitamin K, osteoporosis and degenerative diseases of ageing

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Prognostic and diagnostic value of des-gamma-carboxy prothrombin in liver cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Clinical and molecular insights into the hepatocellular carcinoma tumour marker des‐γ‐carboxyprothrombin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

The circulating inactive form of matrix gla protein is a surrogate marker for vascular calcification in chronic kidney disease: a preliminary report.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Significance of des-gamma-carboxy prothrombin production in hepatocellular carcinoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Identification of four alternatively spliced transcripts of the Ucma/GRP gene, encoding a new Gla-containing protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Matrix gla protein (MGP): an overexpressed and migration-promoting mesenchymal component in glioblastoma.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Exon 2 deletion splice variant of gamma-glutamyl carboxylase causes des-gamma-carboxy prothrombin production in hepatocellular carcinoma cell lines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Vitamin K2 inhibits the growth of hepatocellular carcinoma via decrease of des-gamma-carboxy prothrombin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Metabolism and cell biology of vitamin K

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Gla-rich protein (GRP), a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Pseudoxanthoma elasticum: reduced gamma-glutamyl carboxylation of matrix gla protein in a mouse model (Abcc6-/-).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Ucma--A novel secreted factor represents a highly specific marker for distal chondrocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

The anticancer effects of vitamin K.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Warfarin causes rapid calcification of the elastic lamellae in rat arteries and heart valves

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Metal binding properties of gamma-carboxyglutamic acid. Implications for the vitamin K-dependent blood coagulation proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Ucma is not necessary for normal development of the mouse skeleton

14 July 2018

1 reference

Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification.

21 January 2018

1 reference

Strong prediction of fractures among older adults by the ratio of carboxylated to total serum osteocalcin

21 January 2018

1 reference

Novel conformation-specific antibodies against matrix gamma-carboxyglutamic acid (Gla) protein: undercarboxylated matrix Gla protein as marker for vascular calcification

21 January 2018

1 reference

Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats

21 January 2018

1 reference

Multifunctional Roles for Serum Protein Fetuin-A in Inhibition of Human Vascular Smooth Muscle Cell Calcification

21 January 2018

1 reference

Insights into the association of Gla-rich protein and osteoarthritis, novel splice variants and γ-carboxylation status

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Matrix Gla Protein Inhibits Ectopic Calcification by a Direct Interaction with Hydroxyapatite Crystals

30 October 2018

1 reference

Prognostic value of matrix Gla protein in breast cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052551

Molecular characterization of two paralog genes encoding Gla-rich protein (Grp) in zebrafish

30 October 2018

1 reference

Levels of vitamin K, immunoreactive prothrombin, des-gamma-carboxy prothrombin and gamma-glutamyl carboxylase activity in hepatocellular carcinoma tissue

21 January 2018

1 reference

12 December 2020

Mechanism of the abnormal vitamin K-dependent gamma-carboxylation process in human hepatocellular carcinomas

1 reference

12 December 2020

Vitamin K: the coagulation vitamin that became omnipotent

1 reference

12 December 2020

Serum Markers of Hepatocellular Carcinoma

1 reference

12 December 2020

Vitamin K antagonists in anticoagulant therapy of patients with cancer

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/340216

1 reference

release_f6p6qnc2jnb5nhorqs556ltii4

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/f6p6qnc2jnb5nhorqs556ltii4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4052551

1 reference

29 July 2017

1 reference