Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: possible role of 4-hydroxynonenal (4-HNE). (Q33728403)

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English	Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: possible role of 4-hydroxynonenal (4-HNE).	scientific article

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scholarly article

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Europe PubMed Central

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28 July 2017

Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: possible role of 4-hydroxynonenal (4-HNE). (English)

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Europe PubMed Central

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28 July 2017

Alzheimer's disease

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Antonio Giordano

12

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28 July 2017

Andrea Antonosante

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Andrea Antonosante

9

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Sandra Moreno

6

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Rodolfo Ippoliti

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Rodolfo Ippoliti

11

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Annamaria Cimini

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Annamaria Cimini

13

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Francesco Cecconi

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Francesco Cecconi

7

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Elisabetta Benedetti

1

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Elisabetta Benedetti

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Europe PubMed Central

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28 July 2017

Loredana Cristiano

3

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Loredana Cristiano

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28 July 2017

Alessia Fidoamore

8

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Alessia Fidoamore

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Europe PubMed Central

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28 July 2017

Erica Di Giacomo

4

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Erica Di Giacomo

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Europe PubMed Central

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28 July 2017

Roberta Falcone

10

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Roberta Falcone

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Europe PubMed Central

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28 July 2017

author name string

Barbara D'Angelo

2

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Europe PubMed Central

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28 July 2017

Francesca Fanelli

5

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Europe PubMed Central

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28 July 2017

publication date

4 March 2014

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28 July 2017

number of pages

10

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28 July 2017

13

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28 July 2017

8

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Europe PubMed Central

PubMed publication ID

28 July 2017

1335-1344

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Europe PubMed Central

PubMed publication ID

28 July 2017

Abeta, oxidative stress in Alzheimer disease: evidence based on proteomics studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Oxidative modification of lipoic acid by HNE in Alzheimer disease brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Impact and Therapeutic Potential of PPARs in Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

p75(NTR) expression and nuclear localization of p75(NTR) intracellular domain in spiral ganglion Schwann cells following deafness correlate with cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Extending life span by increasing oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Signal transduction pathways involved in PPARβ/δ-induced neuronal differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

New insights into brain BDNF function in normal aging and Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Oxidative stress and neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

PPARs in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

PPARbeta agonists trigger neuronal differentiation in the human neuroblastoma cell line SH-SY5Y.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Calcium and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

A beta oligomers - a decade of discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Alzheimer's disease: Abeta, tau and synaptic dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Catalytic site-specific inhibition of the 20S proteasome by 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Induction of brain-derived neurotrophic factor in plaque-associated glial cells of aged APP23 transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Expression of glutathione-S-transferase isozyme in the SY5Y neuroblastoma cell line increases resistance to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Lipid peroxidation and biogenic aldehydes: from the identification of 4-hydroxynonenal to further achievements in biopathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Protein-bound acrolein: Potential markers for oxidative stress

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

28 July 2018

Biochemistry and molecular biology of amyloid beta-protein and the mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

PPAR Regulation of Inflammatory Signaling in CNS Diseases

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: possible neuroprotective mechanisms

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

Neuroprotective mechanisms of peroxisome proliferator-activated receptor agonists in Alzheimer’s disease

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

Age-dependent time course of cerebral brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 in APP23 transgenic mice.

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia.

1 reference

https://api.crossref.org/works/10.4161/CC.28295

21 January 2018

Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

30 October 2018

Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

30 October 2018

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049970

30 October 2018

Regional distribution of PPARbeta in the cerebellum of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24621497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/24621497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24621497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.4161/CC.28295

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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