ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway. (Q33719706)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421041 AND SRC:MED&resulttype=core&format=json

26 January 2020

title

ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway (English)

1 reference

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26 January 2020

1 reference

3

1 reference

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26 January 2020

Raquel del Toro Estévez

4

1 reference

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26 January 2020

Thomas Mathivet

5

1 reference

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26 January 2020

António Duarte

6

1 reference

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26 January 2020

Michael Simons

7

1 reference

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26 January 2020

8

Anne Eichmann

1 reference

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26 January 2020

author name string

Bruno Larrivée

1

1 reference

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26 January 2020

Claudia Prahst

2

1 reference

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26 January 2020

language of work or name

English

0 references

publication date

1 March 2012

1 reference

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26 January 2020

number of pages

12

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inferred from page(s)

published in

Developmental Cell

1 reference

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26 January 2020

volume

22

1 reference

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26 January 2020

issue

3

1 reference

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26 January 2020

page(s)

489-500

1 reference

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Notch4 normalization reduces blood vessel size in arteriovenous malformations

26 January 2020

cites work

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Endothelial development taking shape

21 June 2018

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Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo

21 June 2018

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Coordinating cell behaviour during blood vessel formation.

21 June 2018

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Basic and therapeutic aspects of angiogenesis

21 June 2018

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Molecular control of endothelial cell behaviour during blood vessel morphogenesis

21 June 2018

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ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif

21 June 2018

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Controlling angiogenesis by two unique TGF-β type I receptor signaling pathways

21 June 2018

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ALK1 as an emerging target for antiangiogenic therapy of cancer

21 June 2018

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Interaction between alk1 and blood flow in the development of arteriovenous malformations

21 June 2018

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The VEGF-regulated transcription factor HLX controls the expression of guidance cues and negatively regulates sprouting of endothelial cells

21 June 2018

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Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies

21 June 2018

1 reference

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Hereditary haemorrhagic telangiectasia: Pathophysiology, diagnosis and treatment

21 June 2018

1 reference

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Identification and functional analysis of endothelial tip cell-enriched genes

21 June 2018

1 reference

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BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo

21 June 2018

1 reference

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Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia

21 June 2018

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Hereditary hemorrhagic telangiectasia: from molecular biology to patient care.

21 June 2018

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Hypoxia-driven angiogenesis: role of tip cells and extracellular matrix scaffolding.

21 June 2018

1 reference

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ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth

21 June 2018

1 reference

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Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants

21 June 2018

1 reference

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Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

21 June 2018

1 reference

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Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice

21 June 2018

1 reference

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ALK1 signaling regulates early postnatal lymphatic vessel development

21 June 2018

1 reference

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Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia

21 June 2018

1 reference

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Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease

21 June 2018

1 reference

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Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells

21 June 2018

1 reference

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Guidance of vascular development: lessons from the nervous system.

21 June 2018

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Retardation of retinal vascular development in apelin-deficient mice

21 June 2018

1 reference

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Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

21 June 2018

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Bone morphogenetic protein-9 is a circulating vascular quiescence factor

21 June 2018

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ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

21 June 2018

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Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis

21 June 2018

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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

21 June 2018

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The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

21 June 2018

1 reference

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Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

21 June 2018

1 reference

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Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

21 June 2018

1 reference

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Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

21 June 2018

1 reference

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Structural basis for the inhibition of activin signalling by follistatin.

21 June 2018

1 reference

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Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

21 June 2018

1 reference

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Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

21 June 2018

1 reference

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The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

21 June 2018

1 reference

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Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.

21 June 2018

1 reference

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Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

21 June 2018

1 reference

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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

21 June 2018

1 reference

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Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression

21 June 2018

1 reference

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Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels.

21 June 2018

1 reference

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Arteriovenous malformations in mice lacking activin receptor-like kinase-1

21 June 2018

1 reference

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gridlock, an HLH gene required for assembly of the aorta in zebrafish

21 June 2018

1 reference

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Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2.

21 June 2018

1 reference

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BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain.

21 June 2018

1 reference

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Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch.

30 October 2018

1 reference

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Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

30 October 2018

1 reference

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Overlapping spectra of SMAD4 mutations in juvenile polyposis (JP) and JP-HHT syndrome.

30 October 2018

1 reference

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The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

30 October 2018

1 reference

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The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system

30 October 2018

1 reference

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Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling

30 October 2018

1 reference

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Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047762

Robo4 Maintains Vessel Integrity and Inhibits Angiogenesis by Interacting with UNC5B

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047762

Activin receptor-like kinase 1 inhibits human microvascular endothelial cell migration: Potential roles for JNK and ERK

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047762

Molecular defects in rare bleeding disorders: hereditary haemorrhagic telangiectasia

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22421041

12 December 2020

inferred from PubMed ID database lookup

Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22421041

12 December 2020

inferred from PubMed ID database lookup

Laminin-Binding Integrins Induce Dll4 Expression and Notch Signaling in Endothelial Cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22421041

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.DEVCEL.2012.02.005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421041 AND SRC:MED&resulttype=core&format=json

release_ijiv2ch5jnaube2uxq27q2b42u

26 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ijiv2ch5jnaube2uxq27q2b42u

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421041 AND SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

22421041

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421041 AND SRC:MED&resulttype=core&format=json