Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease (Q33713881)

28 July 2017

title

Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease (English)

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28 July 2017

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Yinxing Liu

1

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28 July 2017

Christa Studzinski

2

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28 July 2017

Tina Beckett

3

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28 July 2017

Hanjun Guan

4

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28 July 2017

Matthew A Hersh

5

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28 July 2017

M Paul Murphy

6

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28 July 2017

Ronald Klein

7

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28 July 2017

Louis B Hersh

8

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28 July 2017

publication date

26 May 2009

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28 July 2017

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28 July 2017

volume

17

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28 July 2017

issue

8

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28 July 2017

page(s)

1381-1386

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Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease

28 July 2017

cites work

1 reference

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A dynamic relationship between intracellular and extracellular pools of Abeta

28 July 2018

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Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins

28 July 2018

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Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

28 July 2018

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Aldosterone does not mediate angiotensin II-induced atherosclerosis and abdominal aortic aneurysms

28 July 2018

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LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

28 July 2018

1 reference

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

28 July 2018

1 reference

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Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

28 July 2018

1 reference

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

28 July 2018

1 reference

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

28 July 2018

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Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

28 July 2018

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Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

28 July 2018

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Clearance of amyloid-beta by circulating lipoprotein receptors

30 October 2018

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Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice

30 October 2018

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Subcutaneous Nogo receptor removes brain amyloid-beta and improves spatial memory in Alzheimer's transgenic mice

30 October 2018

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Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

30 October 2018

1 reference

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Tat peptides inhibit neprilysin

30 October 2018

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Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice

30 October 2018

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Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death

30 October 2018

1 reference

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RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

30 October 2018

1 reference

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Mutation of active site residues of the puromycin-sensitive aminopeptidase: conversion of the enzyme into a catalytically inactive binding protein.

30 October 2018

1 reference

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Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.

30 October 2018

1 reference

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Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease

30 October 2018

1 reference

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Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835241

Mechanism of digestion of bradykinin and lysylbradykinin (kallidin) in human serum. Role of carboxypeptidase, angiotensin-converting enzyme and determination of final degradation products

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19471248

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2009.115

1 reference

28 July 2017

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28 July 2017

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